Results 181 to 190 of about 79,223 (263)

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati   +12 more
wiley   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin   +6 more
wiley   +1 more source

Sugars as Central Integrators of Plant Immunity and Stress Responses

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Sugars are fundamental metabolites that sustain plant growth and development, but accumulating evidence demonstrates that they also function as regulatory hubs in plant defence. In this review, we synthesise current knowledge on how carbohydrate dynamics coordinate metabolism, signalling, and structural responses to shape plant resistance ...
Anna Wlazło   +2 more
wiley   +1 more source

The Ash Dieback Pathogen Resists the Chemical Defences of Its Host Tree, European Ash, by Depleting Them From the Growth Medium

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plant pathogenic fungi are major drivers of disease in forest trees, often causing substantial ecological and economic damage. Ash dieback, caused by the ascomycete Hymenoscyphus fraxineus, has resulted in the widespread decline of Fraxinus excelsior populations throughout Europe.
Björn Lichnock   +8 more
wiley   +1 more source

Strategies for GH functional annotation: toward harmonized and predictive CAZymology. [PDF]

open access: yesBiotechnol Biofuels Bioprod
Erdody DS   +4 more
europepmc   +1 more source

Prebiotic Bimuno® GOS reduces illness symptoms and supports gut barrier function and immunity after intermittent exercise in the heat

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise in hot climates increases the risk of gastrointestinal (GI) disruption and respiratory illness. We investigated the effects of a 42 day prebiotic intervention on markers of intestinal epithelial injury, GI discomfort and immunity following football specific exercise in the heat and daily upper respiratory illness.
Connor J. Parker   +6 more
wiley   +1 more source

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