Results 201 to 210 of about 100,249 (308)

Crystal structure of endo‐β‐1,6‐galactanase from Streptomyces avermitilis

Acta Crystallographica Section D, EarlyView.
The crystal structure of S. avermitilis endo‐β‐1,6‐galactanase belonging to GH30 subfamily 5 reveals the first structural framework for endo‐β‐1,6‐galactanase. The β‐1,6‐galactobiose‐bound complex identifies the catalytic subsites and a distal secondary sugar‐binding site, providing insight into β‐1,6‐galactan recognition.Endo‐β‐1,6‐galactanases ...
Zui Fujimoto, Naomi Kishine, Toshihisa Kotake, Satoshi Kaneko   +3 more
wiley   +1 more source

Preclinical development of a well-defined semisynthetic glycoconjugate vaccine against <i>Haemophilus influenzae</i> type b. [PDF]

Sci Adv
Han W, Qin C, Tong W, Yang K, Tian X, Zhang JR, Liu J, Seeberger PH, Hu J, Yin J.   +9 more
europepmc   +1 more source

Effect of Salinity Stress on Gut–Brain–Gonad Axis in the Red‐Eared Slider (Trachemys scripta elegans)

Integrative Zoology, EarlyView.
The increase in salinity leads to changes in the gut microbiota and metabolites of Trachemys scripta elegans, affecting the synthesis and secretion of neurotransmitters or precursors, which can inhibit the secretion of reproductive hormones and affect the self‐renewal and differentiation process of spermatogonial stem cells.
Qiongyu Zhang, Na Li, Xue Tang, Hanru Chen, Meiling Hong, Li Ding   +5 more
wiley   +1 more source

Immunomodulatory Effects of <i>Periplaneta americana</i> Oligosaccharides Through SCFA-Producing Gut Microbiota and Metabolic Regulation in Immunosuppressed Mice. [PDF]

Biomolecules
Lu K, Zhang C, Bao J.
europepmc   +1 more source

Determinants of Immunoglobulin‐G N‐Glycan Patterns in the Aging General Population

Allergy, EarlyView.
The effect of demographic and lifestyle factors on IgG N‐glycosylation, which determines IgG's inflammatory response, remains poorly characterized. Aging, higher BMI, female sex, smoking, and heavy alcohol consumption are determinants of IgG N‐glycome patterns, which are indicative of inflammation. Women exhibit a distinct change in IgG N‐glycosylation
Samantha Leonard, Ralph Heijmans, Virgil A. S. H. Dalm, Silvan Licher, Jan Nouta, Steinar Gijze, David Falck, P. Martin van Hagen, Robin Peeters, Manfred Wuhrer, Layal Chaker   +10 more
wiley   +1 more source

Soybean Oligosaccharides Mitigate HFD-Induced Obesity in Mice with Changes in the Gut Mucus-Microbiota Axis. [PDF]

Nutrients
Zhang J, Zhang N, Chen J, Liu J, Ge Z, Zhou Y, Wang F.   +6 more
europepmc   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Shaping of the Infant Gut Microbiome by Milk Oligosaccharides. [PDF]

Annu Rev Biochem
Federico VA, Cliffel DE, Gaddy JA, Townsend SD.   +3 more
europepmc   +1 more source

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

Allergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura, Jeremy Corriger, Hélène Omer, Marie Bodinier, Dirk Haller, Tomer Hertz, Martin Larsen, Maria Carmen Collado   +7 more
wiley   +1 more source

Glycoinformatic Profiling of Label-Free Intact Heparan Sulfate Oligosaccharides. [PDF]

Mol Cell Proteomics
Maciej-Hulme ML, Kim J, Roberts ET, Zhang Y, van der Velden A, Braanker DD, Yanginlar C, de Graaf M, Rabelink T, van den Berg B, van Ommen E, Maas R, Logt AV, Amster IJ, van der Vlag J.   +14 more
europepmc   +1 more source