Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Impact of fraction size on the efficacy of xylo-oligosaccharides in broiler chicken diets. [PDF]
Anim NutrWallace AD +3 more
europepmc +1 more source
IgE And IgG Antibody Responses to α‐Gal and Association With Carotid Stenosis in Swedish Patients
Allergy, EarlyView.
Marija Perusko +7 more
wiley +1 more source
Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source
Human-Identical Milk Oligosaccharides in Infant Formula: How Close Are We to Evidence-Based Benefit? [PDF]
Adv NutrGolan Y.
europepmc +1 more source
Ecological Entomology, EarlyView.Hamiltonella defensa infection increases honeydew production in certain aphid genotypes, potentially modifying aphid feeding behaviour. Parasitoid wasps, Aphidius ervi, are more attracted to honeydew from H. defensa‐infected aphids; though larger honeydew amounts may slightly deter searching.
Desiré Macheda +5 more
wiley +1 more source
Total synthesis of the capsular polysaccharide repeating unit towards the development of a glycoconjugate vaccine against <i>Klebsiella pneumoniae</i> ST512. [PDF]
Beilstein J Org ChemZhang S, Daněk O, Seeberger PH.
europepmc +1 more source
Discovery of a cryptic aminoacidic triad involved in the temperature adaptation of GH1 enzymes
The FEBS Journal, EarlyView.Cold‐active enzymes retain high catalytic activity at low temperatures but are characterized by thermal instability, a behavior not fully understood. Comparison between a cold‐active GH1 and its mesophilic counterparts highlights the role of a three‐residue motif (W‐M‐F) in conferring structural stability to a mesophilic GH1.
Stefania Digiovanni +5 more
wiley +1 more source
Marine-Derived Neoagarotetraose Alleviates Dry Eye Disease by Suppressing Inflammation and Apoptosis in a Murine Model. [PDF]
Mar DrugsWu N, Du Y, Wu C, Chan Z, Zeng R.
europepmc +1 more source