Results 41 to 50 of about 4,921 (178)

Protective Effects of Fenugreek and Stevia Extracts on Dexamethasone‐Induced Testicular Damage in a Rat Model

Food Safety and Health, EarlyView.
Fenugreek and stevia extracts protect against dexamethasone‐induced testicular damage in male rats by enhancing antioxidant defenses, improving sperm quality, and restoring hormonal balance, highlighting their potential as natural therapeutics for preventing corticosteroid‐induced reproductive toxicity.
Mosab Gad, Medhat Ibrahim A. Omar, Mohammed I. Elkhateeb, Ahmed A. Zaky   +3 more
wiley   +1 more source

Animal modeling methods for oligospermia: A review

Asian Pacific Journal of Reproduction
Oligospermia, characterized by a low sperm count in semen, is a major cause of male infertility and may result from various factors including infections, lifestyle choices, retrograde ejaculation, tumors, hormonal imbalances, drug treatments, and ...
Dinesh Sharma, Nitesh Parsaila, Archana Navale, Sagar Shinde, Nishant Patidar, Prachi Nahar, Ajay Shelke, Nilay Solanki   +7 more
doaj   +1 more source

Study of seminal fluid parameters and fertility of male sickle-cell disease patients and potential impact of hydroxyurea treatment

Journal of Applied Hematology, 2016
Context: Male sickle-cell disease (SCD) patients often have moderate to severe hypogonadism resulting in abnormal seminal fluid parameters. Hydroxyurea (HU) used in SCD patients has been found to further aggravate the testicular dysfunction.
Lulup K Sahoo, Bipin K Kullu, Siris Patel, Pragyan Rout, Nayan K Patel, Prasanta Purohit, Satyabrata Meher   +6 more
doaj   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Screening of mutations and polymorphism in CFRT gene in men infertile due to oligo- or azospermia [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2002
We concluded that CFTR gene plays a role in the etiology of obstructive azoospermia and that it also could be involved in same cases of impaired spermatogenesis and sperm maturation.
Kušić Jelena S., Radojković Dragica P., Maletić-Vukotić Vinka D., Branković Snežana, Savić Ana P.   +4 more
doaj   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

Andrology, EarlyView.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu, Meng‐Li Cui, Wen‐Jing Yuan, Jia‐Ning Zhang, Shuo Zhang, Xi‐Qiao Yao, Ruo‐Qing Li, Jin‐Feng Li, En‐Zhong Li   +8 more
wiley   +1 more source

Elevated CD4+, CD8+, and Pro-inflammatory Cytokine Levels and H19 Hypomethylation are Associated with Reduced Sperm Motility in Oligoasthenoteratozoospermia: A Case-control Study

Dubai Medical Journal
Introduction: Oligoasthenoteratozoospermia (OAT) is a frequent cause of male reproductive issues, but its etiology remains unclear. This study investigated the associations between immune markers, epigenetic alterations, and sperm parameters in men with
Rehab Sh. Al-Maliki
doaj   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Do Infections Cause Oligospermia and Could Empiric Antibiotics Antiprotozoal and Antifungal Treat Oligospermia?

Gynecology Obstetrics & Reproductive Medicine, 2014
OBJECTIVE: Previous studies have shown some factors that contribute to the idiopathic oligospermia which is not significantly enough to have a definite treatment for oligospermia.
Mohammed Nabil Dajanı
doaj  

Influence of Arginine on Oligospermia

Experimental Biology and Medicine, 1947
Summary1. Eighteen infertile men with oligospermia received 1.8-2.7 g of arginine and minimal amounts of lysine, pyridoxine, and tryptophane in tablet form for 8 months.2. The tendency for sperm concentration to increase was as great in the untreated group as in the treated groups.3. Although no pregnancies occurred in the treated groups, 2 pregnancies
openaire   +2 more sources