Results 51 to 60 of about 9,493 (210)

Screening of mutations and polymorphism in CFRT gene in men infertile due to oligo- or azospermia [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2002
We concluded that CFTR gene plays a role in the etiology of obstructive azoospermia and that it also could be involved in same cases of impaired spermatogenesis and sperm maturation.
Kušić Jelena S., Radojković Dragica P., Maletić-Vukotić Vinka D., Branković Snežana, Savić Ana P.   +4 more
doaj   +1 more source

Infertility and hypergonadotropic hypogonadism as first evidence of hereditary apolipoprotein A-I amyloidosis [PDF]

, 2007
Purpose: We report that primary infertility and hypergonadotropic hypogonadism in young patients may be caused by testicular amyloidosis and it is associated with the presence of a mutation in the apoA-I gene, resulting in the replacement of proline for ...
BIASI L, F. SCOLARI, GREGORINI G, MARTINI PR, MERLINI G, OBICI L, SCALVINI T, TARDANICO R   +7 more
core   +1 more source

RAD21L1 Is Sufficient and Effective for Reprogramming Human Sertoli Cells to Phenotypic Spermatogonial Stem Cells Through DNA Methylation and Essential for Male Fertility

Advanced Science, Volume 12, Issue 45, December 4, 2025.
RAD21L1 is upregulated in human Sertoli cells to be transited to become spermatogonial stem cells by overexpressing DAZ family three genes. RAD21L1 is sufficient and effective for reprogramming Sertoli cells into human spermatogonial stem cells with high safety through DNA methylation.
Caimei He, Yinghong Cui, Wei Chen, Chunyun Li, Zuping He   +4 more
wiley   +1 more source

Hi‐LabSpermTracking: A Novel and High‐Quality Sperm Tracking Dataset with an Advanced Ensemble Detection and Tracking Approach for Real‐World Clinical Scenarios

Advanced Intelligent Systems, Volume 7, Issue 12, December 2025.
This study presents Hi‐LabSpermTracking, a long‐duration, expert‐annotated sperm motility dataset for detection and tracking. It evaluates You Only Look Once version 8, Real‐Time Detection Transformer, and Simple Online and Realtime Tracking with a Deep Association Metric in three scenarios. The mean ensemble method improves tracking performance. Sperm
Abdulsamet Aktas, Gorkem Serbes, Hakkı Uzun, Merve Huner Yigit, Nizamettin Aydin, Hamza Osman Ilhan   +5 more
wiley   +1 more source

Pattern of seminal fluid analysis in a male partner of infertile couple presented in infertility clinic of Patan hospital

Journal of Pathology of Nepal, 2021
Background: Infertility is defined as the failure of a couple to conceive after one year of regular sexual intercourse. The malefactor is responsible for at least 50% of cases of failure to conceive.
Dipti Gautam, Manisha Shrestha, Shiva Raj K.C.   +2 more
doaj   +1 more source

Dermatoglyphics in patients with oligo/azospermia [PDF]

, 2005
The study of patterns of fingerprints is important in anthropology and medical genetics, chiefly because of their diagnostic usefulness. In the present work, we studied the frequencies of various types of skin ridges of the first phalanx in patients with
Farhud, D.D., Hashemzadeh-Chaleshtori, Morteza., Pour-Jafari, Hamid.   +2 more
core   +2 more sources

P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders

Medicine Bulletin, Volume 1, Issue 2, Page 121-135, December 2025.
ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley   +1 more source

Steroid Hormones and Endocrine Disruptors: Recent Advances in Receptor–Mediated Actions [PDF]

, 2017
It has been accepted that receptor-mediated action of steroid hormones depends on both the receptor and the hormonal level. The mechanism of transcription by steroid receptors is mediated by cofactors, which function as co-activators or co ...
Indarto, Dono, Izawa, Masao
core  

Update and new advances in fertility preservation and cancer

CA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 602-629, November/December 2025.
Abstract Adolescents and young adults with a cancer diagnosis face unique challenges during treatment and into survivorship related to fertility and family building. This review provides an updated overview of the impact of cancer and its associated treatments, including novel treatments in male and female fertility.
Gwendolyn P. Quinn, Michelle Bayefsky, Brooke Cherven, Lauren V. Ghazal, Kara N. Goldman, Nina Francis Levin, Leena Nahata, Bobby Najari, Sameer Thakker, Daniel R. Greenberg, Joshua A. Halpern, Susan T. Vadaparampil   +11 more
wiley   +1 more source

Preimplantation Testing of Human Blastomeres for Aneuploidy Increases IVF Success in Couples Where Male Partners Had Abnormal Semen Parameters

Biomedicines
Background/Objectives: Male infertility is becoming a serious problem affecting about 7% of all men worldwide and is a major or contributory factor in 50% of infertile couples overall.
Mahira Ismayilova, Aytakin Hasanova, Andrei Semikhodskii   +2 more
doaj   +1 more source