Results 21 to 30 of about 9,054 (246)

Homozygous mutation in the prokineticin-receptor2 gene (Val274Asp) presenting as reversible Kallmann syndrome and persistent oligozoospermia: case report. [PDF]

, 2008
Prokineticin 2 (Prok2) or prokineticin-receptor2 (Prok-R2) gene mutations are associated with Kallmann syndrome (KS). We describe a new homozygous mutation of Prok-R2 gene in a man displaying KS with an apparent reversal of hypogonadism.
Asci R, Bellastella A, Bellastella G, De Bellis A, ELEFANTE, ANDREA, Esposito D, IOLASCON, ACHILLE, Maione L, Sinisi AA   +8 more
core   +1 more source

Kromosoomianomaaliad ja kromosoomivariandid infertiilsetel meestel [PDF]

, 2006
Lastetust esineb umbes 15% peredest. Selle mehepoolsetest põhjustest moodustavad 30% geneetilised tegurid, eeskätt kromosoomihaigused. Eestis on viljatuse tsütogeneetilisi põhjusi seni vähe uuritud.
Lissitsina, Jelena, Mikelsaar, Ruth, Punab, Margus   +2 more
core   +2 more sources

Prevalence of Y chromosome deletions in a Brazilian population of nonobstructive azoospermic and severely oligozoospermic men [PDF]

, 2003
We determined the prevalence of Y chromosome deletions in a population of 60 Brazilian nonobstructive azoospermic and severely oligozoospermic men. PCR-based screening of microdeletions was performed on lymphocyte DNA for the presence of 14 sequence ...
Avellar, Maria Christina Werneck, Cedenho, Agnaldo Pereira, Fraietta, Renato, Porto, Catarina Segreti, Spaine, Deborah Montagnini, Srougi, Miguel, São Pedro, Simone Lima   +6 more
core   +2 more sources

Chromosomal Abnormalities in Infertile Men from Southern India [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background and Objective: Male infertility has been associated with aneuploidies and structural chromosomal abnormalities, Yq microdeletions and specific gene mutations and/or polymorphisms.
Jaganathan Suganya, Smita B Kujur, Kamala Selvaraj, Muthiah S. Suruli, Geetha Haripriya, Chandra R. Samuel   +5 more
doaj   +1 more source

Tissue specific age acceleration patterns in the sperm of oligozoospermic men

Frontiers in Reproductive Health, 2022
To determine if disease can modify aging patterns in an affected tissue without altering the aging patterns of other tissues, blood and semen of individuals with oligozoospermia (n = 10) were compared to the blood and semen of individuals with ...
Kelaney Stalker, Chad Pollard, Kenneth Aston, Tim Jenkins, Tim Jenkins   +4 more
doaj   +1 more source

Meiotic recombination and male infertility: from basic science to clinical reality? [PDF]

, 2011
Infertility is a common problem that affects approximately 15% of the population. Although many advances have been made in the treatment of infertility, the molecular and genetic causes of male infertility remain largely elusive. This review will present
Hann, Michael C., Lau, Patricio E., Tempest, Helen G.   +2 more
core   +1 more source

Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies [PDF]

, 2018
SOX8 is an HMG-box transcription factor closely related to SRY and SOX9. Deletion of the gene encoding Sox8 in mice causes reproductive dysfunction but the role of SOX8 in humans is unknown.
Achermann, JC, Almstrup, K, Bashamboo, A, Bignon-Topalovic, J, Brauner, R, Chantot-Bastaraud, S, Charreau, EH, Chiauzzi, VA, Christin-Maitre, S, Dain, L, de Malleray Pichard, C, Dumargne, M-C, Duncan, AJ, Eozenou, C, Fusee, L, Hyon, C, Jauch, R, Louis-Sylvestre, C, MacGowan, S, Mazen, I, McElreavey, K, McLean, WHI, Patin, E, Persani, L, Portnoi, M-F, Rajkovic, A, Rajpert-De Meyts, E, Ravel, C, Reyes-Mugica, M, Rojo, S, Rossetti, R, Rouba, H, Schluth-Bolard, C, Siffroi, J-P, Srivastava, Y, Validire, P, Witchel, SF, Yatsenko, SA   +37 more
core   +12 more sources

Seminal Fluid Metabolomic Markers of Oligozoospermic Infertility in Humans

Metabolites, 2020
Infertility affects 12−15% of couples worldwide, and male factors are the cause of nearly half of all cases. Studying seminal fluid composition could lead to additional diagnostic accuracy and a better understanding of the pathophysiology of male ...
Federica Murgia, Valentina Corda, Marianna Serrenti, Valeria Usai, Maria Laura Santoru, K. Joseph Hurt, Mauro Passaretti, Maria Carla Monni, Luigi Atzori, Giovanni Monni   +9 more
doaj   +1 more source

Serum inhibin B as a marker of spermatogenesis [PDF]

, 1998
Inhibin B is produced by Sertoli cells, provides negative feedback on FSH secretion, and may prove to be an important marker for the functioning of seminiferous tubules.
Jong, F.H. (Frank) de, Pierik, F.H. (Frank), Stijnen, Th. (Theo), Vreeburg, J.T.M. (Jan), Weber, R.F.A. (Robert)   +4 more
core   +4 more sources

SAT-158 Azoospermia/Oligozoospermia and Prostate Cancer are Increased in Families of Women with Primary Ovarian Insufficiency [PDF]

J Endocr Soc
Kristina Allen‐Brady, Samantha Kodoma, Lauren Verrilli, Joemy M Ransay, Erica Johnstone, Joshua J. Horns, Benjamin R Emery, Lisa Cannon‐Albright, Kenneth I. Aston, James M. Hotaling, Corrine K. Welt   +10 more
europepmc   +3 more sources