Results 81 to 90 of about 11,390 (207)
Comparison of First-Line Dual Combination Treatments in Hypertension: Real-World Evidence from Multinational Heterogeneous Cohorts. [PDF]
, 2020 Background and objectives: 2018 ESC/ESH Hypertension guideline recommends 2-drug combination as initial anti-hypertensive therapy. However, real-world evidence for effectiveness of recommended regimens remains limited.
Cho, Jaehyeong +10 more
core +2 more sources
Reduced Descending Itch Inhibition in Peripheral Neuropathy Patients With Chronic Pruritus
European Journal of Pain, Volume 30, Issue 1, January 2026.ABSTRACT Background Peripheral neuropathies (PNP) cause a wide range of symptoms of which pruritus and pain are a major burden to patients. Clarifying their mechanisms will facilitate the adequate symptom management. In contrast to neuropathic pain, neuropathic pruritus has long been understudied.
Jonas Eck +9 more
wiley +1 more source
Seronegative Intestinal Villous Atrophy: A Diagnostic Challenge
Case Reports in Gastrointestinal Medicine, 2016 Celiac disease is the most important cause of intestinal villous atrophy. Seronegative intestinal villous atrophy, including those that are nonresponsive to a gluten-free diet, is a diagnostic challenge.
Cláudio Martins +10 more
doaj +1 more source
Overexpression of long non-coding RNA NORAD promotes invasion and migration in malignant melanoma via regulating the MIR-205-EGLN2 pathway. [PDF]
, 2019 Growing evidence suggests that long non-coding RNAs NORAD and miR-205 play a significant role in regulating cancer progression and metastasis. In this study, high expression of NORAD was firstly observed in melanoma tissues and human malignant melanoma ...
Cao, Ke +10 more
core +1 more source
Learning Health Systems, Volume 10, Issue 1, January 2026.ABSTRACT Introduction Despite strong evidence supporting guideline‐directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF), a significant gap persists in the consistent application of these therapies. This shortfall has prompted organizations like the American College of Cardiology to recommend leveraging electronic ...
Joey LeGrand +5 more
wiley +1 more source
Journal of Pharmacological Sciences, 2013 Angiotensin II (Ang II) infusion into rats elevates local angiotensin II levels through an AT1 receptor–dependent pathway in the kidney. We examined whether treatment with an angiotensin-converting enzyme (ACE) inhibitor, temocapril, or an AT1-receptor ...
Keisuke Ohnishi +12 more
doaj +1 more source
Antagonistas da angiotensina II: experiência clínica com o tratamento da hipertensão, prevenção de desfechos cardiovasculares e proteção renal na nefropatia diabética e proteinúria [PDF]
, 2006 Angiotensin II antagonists (AIIAs) were introduced to treat hypertension about 10 years ago. During this period they were evaluated not only in terms of efficacy and safety but also in several large studies with clinical outcomes. They are efficacious in
Gavras, Haralambos +1 more
core +4 more sources
Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.Phaeochromocytomas and paragangliomas (PPGLs) are catecholamine‐secreting neuroendocrine tumours (NETs) of the adrenal medulla and autonomic nervous system. Early recognition and management is critical given their potential morbidity and mortality. For this reason, stand‐alone screening investigations rely on a low diagnostic threshold, achieving high ...
Maria Hadjicosti +6 more
wiley +1 more source
Using electronic health records to support clinical trials: a report on stakeholder engagement for EHR4CR [PDF]
, 2015 Background. The conduct of clinical trials is increasingly challenging due to greater complexity and governance requirements as well as difficulties with recruitment and retention.
Dugas, Martin +7 more
core +6 more sources
Exploring metabolic dysfunction in chronic kidney disease [PDF]
, 2012 Impaired kidney function and chronic kidney disease (CKD) leading to kidney failure and end-stage renal disease (ESRD) is a serious medical condition associated with increased morbidity, mortality, and in particular cardiovascular disease (CVD) risk ...
Slee, Adrian D.
core +2 more sources