Results 51 to 60 of about 4,063 (129)
Abstract INTRODUCTION Face identification algorithms have increased the risk of study participants being identified through different neuroimaging modalities. De‐facing algorithms can de‐identify neuroimages; however, none are validated in individuals with Down syndrome (DS) – a population at high risk of Alzheimer's disease and the focus of numerous ...
Jason K. Russell +8 more
wiley +1 more source
Abnormal amyloid PET usually represents intermediate/high Alzheimer's disease neuropathologic change
Abstract INTRODUCTION Alzheimer's disease neuropathologic change (ADNC) classification identifies not/low and intermediate/high levels of neuropathology. Our goal was to assess how frequently a positive amyloid positron emission tomography (PET) scan indicates not/low ADNC and whether this autopsy finding can occur >10 years after a positive amyloid ...
Brian J. Burkett +16 more
wiley +1 more source
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) represent a unique clinical syndrome affecting up to 80% of PSC patients, characterised by distinct epidemiological patterns, pathophysiological mechanisms and clinical outcomes that differ substantially from either condition occurring independently ...
Luisa Bertin +7 more
wiley +1 more source
Associations Between Metabolic Dysregulation and Stage B Heart Failure in Hispanic Populations
Stage B heart failure, marked by LV abnormalities and diastolic dysfunction, is relatively common in asymptomatic Hispanics. Obesity, hypertension, and metabolic syndrome are closely linked to LV hypertrophy or dysfunction, suggesting targeted interventions for this group may be beneficial. ABSTRACT Background Left ventricular structural abnormalities (
Miryoung Lee +6 more
wiley +1 more source
Abstract BACKGROUND The current biomarker framework for the diagnosis and staging of Alzheimer's disease (AD) relies mainly on neuropathological features; thus, its performance for diagnosis is limited prior to the initiation of neurodegeneration. Here, we leveraged transcriptomic data to develop a new framework for omic‐informed blood‐based diagnostic
Michael W. Lutz +4 more
wiley +1 more source
Epidemiology of Progressive Supranuclear Palsy in Navarre, Spain: A Population‐Based Study
This population‐based observational retrospective epidemiological study on PSP in Navarre for 13 years represents the first in Spain and the first with application of the new MDS diagnostic criteria in Europe. It yielded 226 prevalent PSP cases. Age‐standardized point prevalence rate was 7.52/100,000 inhabitants, and age‐standardized annual incidence ...
P. Arrondo Gómez +8 more
wiley +1 more source
Tau PET overlap index correlation with neuropathological findings
Abstract INTRODUCTION The tau positron emission tomography (PET) overlap index (OI) has shown promise in maximizing signal‐to‐noise for longitudinal tau PET imaging, particularly for early tau pathology, but requires validation against neuropathology.
Seokbeen Lim +27 more
wiley +1 more source
Defining Recovery and Relapse in Bulimia Nervosa: A Systematic Review of the Literature
ABSTRACT Objective Despite advances in understanding bulimia nervosa (BN), standardized definitions of outcome stages remain lacking. This review aims to synthesise definitions of recovery and relapse in BN to improve its assessment and comparability across study outcomes. Methods A systematic review was conducted using PRISMA guidelines.
Valentina Gardini +2 more
wiley +1 more source
ABSTRACT Background Endoscopic retrograde cholangiopancreatography (ERCP) is a procedure that combines x‐ray and upper gastrointestinal (GI) endoscopy for diagnosis and treatment of pancreatic and biliary diseases. Cholangitis is the main infectious complication after ERCP surgery.
Shiwen Huang +6 more
wiley +1 more source
Long‐Term Outcomes in Patients With Turner Syndrome: A 68‐Year Follow‐Up
Background Turner syndrome (TS) is the most common sex chromosome abnormality in women and is associated with increased morbidity and mortality. We describe long‐term outcomes in a large cohort of patients with TS.
Margaret M. Fuchs +4 more
doaj +1 more source

