Abstract INTRODUCTION Research is limited regarding meaningful change thresholds for individual patients on clinical outcome assessments (COAs) frequently used in clinical trials for Alzheimer's disease and related dementias (ADRD), particularly in population‐based studies early in the disease course.
Jeremiah A. Aakre +8 more
wiley +1 more source
Case Report and Literature Review: Interventional Management of Erythromelalgia. [PDF]
Erythromelalgia is a rare and very difficult to treat pain syndrome that usually presents as severe bilateral burning pain in the extremities. Here we present a case of a 34-year-old female with erythromelalgia who we treated successfully with a lumbar ...
Chinn, Gregory, Guan, Zhonghui
core
Impact of neonatal intensive care bed configuration on rates of late-onset bacterial sepsis and methicillin-resistant Staphylococcus aureus colonization [PDF]
OBJECTIVES: Infections cause significant morbidity and mortality in neonatal intensive care units (NICUs). The association between nursery design and nosocomial infections has not been delineated. We hypothesized that rates of colonization by methicillin-
Burnham, Carey-Ann D +6 more
core +2 more sources
Abstract INTRODUCTION Temporal cortical microstructural changes precede cortical atrophy during memory decline. We used neurite orientation dispersion and density imaging (NODDI) to assess such early microstructural change. METHODS Cognitively unimpaired (CU, n = 725) and mildly cognitively impaired (MCI, n = 111) participants from the Mayo Clinic ...
Jay J. Pillai +9 more
wiley +1 more source
Long‐Term Outcomes in Patients With Turner Syndrome: A 68‐Year Follow‐Up
Background Turner syndrome (TS) is the most common sex chromosome abnormality in women and is associated with increased morbidity and mortality. We describe long‐term outcomes in a large cohort of patients with TS.
Margaret M. Fuchs +4 more
doaj +1 more source
Functional bowel disease : a challenging frontier in gastroenterology [PDF]
The last 30 years have seen incredible advances in the science and practice of gastroenterology and hepatology. In the 1970s, the fiberoptic endoscopic revolution facilitated the visualization of the mucosa of a large segment of the gastrointestinal ...
Camilleri, Michael
core
Prevalence of Symptomatic Heart Failure with Reduced and with Normal Ejection Fraction in an Elderly General Population-The CARLA Study [PDF]
Background/Objectives: Chronic heart failure (CHF) is one of the most important public health concerns in the industrialized world having increasing incidence and prevalence.
A Azevedo +56 more
core +4 more sources
Who is really at risk? Identifying risk factors for subthreshold and full syndrome eating disorders in a high-risk sample [PDF]
BACKGROUND: Numerous longitudinal studies have identified risk factors for the onset of most eating disorders (EDs). Identifying women at highest risk within a high-risk sample would allow for focusing of preventive resources and also suggests different ...
Barr Taylor, C. +5 more
core +2 more sources
Hypertensive disorders of pregnancy and neuroimaging markers of dementia risk: A pilot study
Abstract Background and Objectives Hypertensive disorders of pregnancy (HDP) are associated with a long‐term risk of maternal cognitive decline. Limited data exist regarding maternal brain structure in midlife after HDP. We examined the association between prior HDP and neuroimaging markers associated with microvascular brain injury, detected on high ...
Mohamad J. Alshikho +22 more
wiley +1 more source

