Results 151 to 160 of about 853 (171)

Breaking the mould: challenging the status quo of clinical trial response definitions for invasive fungal diseases – a debate

Hoenigl, Martin, Lass-Flörl, Cornelia, Maertens, Johan, Richardson, Malcolm, Slavin, Monica, THOMPSON III, George R.   +5 more
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Genomic Insights of <i>Candida krusei</i>, an Emerging Fungal Pathogen With Intrinsic Antifungal Resistance. [PDF]

Open Forum Infect Dis
Jain K, Wadhwa K, Malik M, Haque S, Prieto MA, Kaur H.   +5 more
europepmc   +1 more source

Antifungal treatment strategies and their impact on resistance development in clinical settings. [PDF]

J Antimicrob Chemother
Van Rhijn N, White PL.
europepmc   +1 more source

Clinical aspects and recent advances in fungal diseases impacting human health. [PDF]

J Antimicrob Chemother
Pagano L, Fernández OM.
europepmc   +1 more source

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Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo

Antimicrobial Agents and Chemotherapy, 2021
Superficial fungal infections are prevalent worldwide, with dermatophytes as the most common cause. Various antifungal agents including azoles and allylamines are commonly used to treat dermatophytosis.
Esmat Mirbzadeh Ardakani, Atefeh Sharifirad, Nasrin Pashootan, Mahsa Nayebhashemi, Mozhgan Zahmatkesh, Somayeh Enayati, Mehdi Razzaghi-Abyaneh, Vahid Khalaj   +7 more
openaire   +2 more sources

In Vivo Efficacy of Olorofim against Systemic Scedosporiosis and Lomentosporiosis

Antimicrobial Agents and Chemotherapy, 2021
Clinically relevant members of the Scedosporium / Pseudallescheria species complex and Lomentospora prolificans are generally resistant against currently available systemic antifungal agents in vitro , and infection due to these species is ...
S. Seyedmousavi, Y. C. Chang, J. H. Youn, D. Law, M. Birch, J. H. Rex, K. J. Kwon-Chung   +6 more
openaire   +2 more sources

Prolonged Remission of Azole-Resistant Lung Aspergillosis with Olorofim, in an Adolescent with X-Linked Chronic Granulomatous Disease

Journal of Clinical Immunology, 2023
Little is known about localized osteoarticular Scedosporiosis (LOS). Most data come from case reports and small case series. Here we present an ancillary study of the nationwide French Scedosporiosis Observational Study (SOS), describing 15 consecutive cases of LOS diagnosed between January 2005 and March 2017. Adult patients diagnosed with LOS defined
Michel, Victor, Mahlaoui, Nizar, Bougnoux, Marie Elisabeth, Garcia-Hermoso, Dea, Lanternier, Fanny, Lévy, Romain   +5 more
openaire   +2 more sources

Antagonistic in vitro interaction between olorofim and voriconazole against Aspergillus fumigatus

Journal of Antimicrobial Chemotherapy
Abstract Background and objectives The emergence of azole resistance among Aspergillus fumigatus isolates has driven the development of novel antifungal compounds, which may potentially be used in combination with existing antifungal drugs.
Illan Laloum, Anne-Laure Bidaud, Elise Recalt, Patrick Schwarz, Marie-Elisabeth Bougnoux, Eric Dannaoui   +5 more
openaire   +1 more source