Results 71 to 80 of about 853 (171)

Appearance of Environment‐Linked Azole Resistance in the Aspergillus fumigatus Complex in New Zealand

open access: yesMycoses, Volume 68, Issue 8, August 2025.
ABSTRACT Background Until 2020, azole resistance in Aspergillus fumigatus complex isolates in New Zealand was due to cyp51A hot spot mutations. This report details the appearance of environment‐linked tandem repeat (TR)‐related azole resistance genotypes since 2021. Methods Isolates were tested by broth micro‐dilution.
Arthur J. Morris   +5 more
wiley   +1 more source

The importance of antimicrobial resistance in medical mycology. [PDF]

open access: yes, 2022
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global health care priority. Some analyses, including the O'Neill report, have predicted that deaths due to drug-resistant bacterial infections may eclipse the total number ...
Berman, J   +11 more
core   +2 more sources

Antifungal Resistance in Non‐fumigatus Aspergillus Species

open access: yesMycoses, Volume 68, Issue 4, April 2025.
ABSTRACT This review provides an in‐depth exploration of antifungal resistance in non‐fumigatus Aspergillus species, mainly focusing on acquired resistance. The available data have been compiled and sometimes re‐analysed. It highlights the increasing prevalence of resistance in non‐fumigatus species belonging to Flavi, Terrei, Nigri, and Nidulantes ...
Elie Djenontin   +3 more
wiley   +1 more source

The performance and costs of XTT, resazurin, MTS and luciferin as viability dyes in in vitro susceptibility testing of Madurella mycetomatis [PDF]

open access: yes
Background: in vitro susceptibility testing for the non-sporulating fungus Madurella mycetomatis is performed with a hyphal suspension as starting inoculum and a viability dye for endpoint reading.
Eadie, Kimberly   +4 more
core   +4 more sources

Investigating a novel antifungal drug that inhibits fatty acid desaturation [PDF]

open access: yes, 2020
Invasive fungal infections represent a group of diseases that are of increasing worldwide concern. This group of diseases is associated with high mortality rates that can be attributed to widespread clinical drug resistance.
Murphy, Sarah
core  

Lactams Exhibit Potent Antifungal Activity Against Monospecies and Multispecies Interkingdom Biofilms on a Novel Hydrogel Skin Model

open access: yesAPMIS, Volume 133, Issue 1, January 2025.
ABSTRACT Infections of intact and damaged skin barriers and keratin are frequently associated with complex biofilm communities containing bacteria and fungi, yet there are limited options for successful management. This study intended to focus on the utility of some novel proprietary lactam molecules, quorum sensing (QS)–derived halogenated furanones ...
Hafsa Abduljalil   +8 more
wiley   +1 more source

Aspergillus fumigatus strains that evolve resistance to the agrochemical fungicide ipflufenoquin in vitro are also resistant to olorofim

open access: yesNature Microbiology, 2023
Abstract Widespread use of azole antifungals in agriculture has been linked to resistance in the pathogenic fungus Aspergillus fumigatus . We show that exposure of A. fumigatus to the agrochemical fungicide, ipflufenoquin, in vitro can
Norman van Rhijn   +5 more
openaire   +4 more sources

The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies

open access: yesChemical Biology &Drug Design, Volume 105, Issue 1, January 2025.
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley   +1 more source

Advances in lung transplantation: 60 years on

open access: yesRespirology, Volume 29, Issue 6, Page 458-470, June 2024.
Abstract Lung transplantation is a well‐established treatment for advanced lung disease, improving survival and quality of life. Over the last 60 years all aspects of lung transplantation have evolved significantly and exponential growth in transplant volume.
Miranda A. Paraskeva, Gregory I. Snell
wiley   +1 more source

Action Mechanisms of Medicinal Plant Components as Antimycosis: A Literature Review [PDF]

open access: yes
Mycosis poses a significant threat to global health, particularly in immune-compromised individuals, and the rise of antifungal resistance has further complicated their treatment.
Abusalim, Ghadah S.   +3 more
core   +2 more sources

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