Results 81 to 90 of about 895 (178)

Lactams Exhibit Potent Antifungal Activity Against Monospecies and Multispecies Interkingdom Biofilms on a Novel Hydrogel Skin Model

APMIS, Volume 133, Issue 1, January 2025.
ABSTRACT Infections of intact and damaged skin barriers and keratin are frequently associated with complex biofilm communities containing bacteria and fungi, yet there are limited options for successful management. This study intended to focus on the utility of some novel proprietary lactam molecules, quorum sensing (QS)–derived halogenated furanones ...
Hafsa Abduljalil, Om Alkhir Alshanta, Safa Chougule, Mark Butcher, Bryn Short, William McLean, Neil Parry, Joanne O'Keeffe, Gordon Ramage   +8 more
wiley   +1 more source

FUNGAL INFECTIONS ASSOCIATED WITH COVID-19 [PDF]

, 2021
To study fungal infections such as Mucormycosis, Aspergillosis, Candidiasis, Cryptococcosis associated with Covid-19. A detailed study was done with the information gathered from the articles in specified databases, online sources, and online published ...
AGARWAL, RICHA, ASIJA, RAJESH, SHARMA, ANTA, TANWAR, SONIKA   +3 more
core   +1 more source

The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies

Chemical Biology &Drug Design, Volume 105, Issue 1, January 2025.
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley   +1 more source

Primary antifungal prophylaxis in hematological malignancies. Updated clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL). [PDF]

At the 10th European Conference on Infections in Leukaemia (ECIL), the guidelines for antifungal prophylaxis in pediatric and adult patients with hematological malignancies (HM) were updated and some changes introduced.
Blennow, O., Blijlevens, N.M.A., Busca, A., Cordonnier, C., Lamoth, F., Maertens, J., Maschmeyer, G., Pagano, L., Spadea, M., Xhaard, A.   +9 more
core   +1 more source

Advances in lung transplantation: 60 years on

Respirology, Volume 29, Issue 6, Page 458-470, June 2024.
Abstract Lung transplantation is a well‐established treatment for advanced lung disease, improving survival and quality of life. Over the last 60 years all aspects of lung transplantation have evolved significantly and exponential growth in transplant volume.
Miranda A. Paraskeva, Gregory I. Snell
wiley   +1 more source

What is the role of microbial biotechnology and genetic engineering in medicine?

MicrobiologyOpen, Volume 13, Issue 2, April 2024.
Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley   +1 more source

New and emerging options for management of invasive fungal diseases in paediatric patients

Mycoses, Volume 67, Issue 1, January 2024.
Abstract Invasive fungal diseases (IFDs) play an important role in the supportive care of paediatric patients with acute leukaemia and those undergoing allogeneic haematopoietic cell transplantation, and they are associated with significantly decreased overall survival rates in affected individuals.
Andreas H. Groll, Katharina Körholz, Malcolm Holterhus, Thomas Lehrnbecher   +3 more
wiley   +1 more source

Knowledge Mapping of Aspergillus‐Related Research in Respiratory Medicine: A Bibliometric Analysis Based on English‐Language Articles Spanning 1975 to 2022

Canadian Respiratory Journal, Volume 2024, Issue 1, 2024.
Background: Aspergillus has become the second most common causative agent of invasive fungal infections and is the leading cause of death from fungal infections. Methods: English‐language publications ranging from 1975 to 2022 collected from the Web of Science Core Collection database were analyzed visually using VOSviewer, R package Bibliometrix ...
Fan Jiang, Xuemei Li, Qing Qiao, Ge Zhang, Yanmei Zhang, Lin Su, Alexandru Corlateanu   +6 more
wiley   +1 more source

Endocarditis caused by Scopulariopsis brevicaulis with disseminated emboli and multiple vascular aneurysms: A case report and literature review

IDCases
Background: Scopulariopsis brevicaulis, a saprophytic fungus often associated with onychomycosis, has seldom been reported to cause deep-tissue infections in immunocompromised patients.
Kieffer Korvin, Myriam Chiarruzi, Aurélie Martin, Clara Gromoff, Vlad Ciobotaru, Milène Sasso, Marie-Clothilde Brunet, Romaric Larcher, Paul Loubet   +8 more
doaj   +1 more source

Triazole-resistant Aspergillus fumigatus in the Netherlands between 1994 and 2022:a genomic and phenotypic study [PDF]

Background: Aspergillus fumigatus is the main cause of invasive aspergillosis and triazole antifungals are the primary treatment option. The effectiveness of triazole therapy is hampered by the emergence of resistance, mainly caused by mutations in the ...
Bosch, Thijs, Buil, Jochem B, Ergün, Mehmet, Li, Ruoyu, Melchers, Willem J G, Rhodes, Johanna, Song, Yinggai, Tehupeiory-Kooreman, Marlou, Verweij, Paul E., Zhang, Jianhua, Zoll, Jan   +10 more
core   +1 more source