Results 71 to 80 of about 895 (178)

Clinical Relevance and Characteristics of Aspergillus calidoustus and Other Aspergillus Species of Section Usti. [PDF]

, 2020
The Aspergilli of section Usti (group ustus) are represented by over 20 species, of which Aspergillus calidoustus is the most relevant human pathogen. Invasive aspergillosis (IA) caused by these fungi is rare but could represent an emerging issue among ...
Erard, V., Glampedakis, E., Lamoth, F.
core   +1 more source

Breakthrough Invasive Mould Infections Under Posaconazole Prophylaxis in Patients With Haematologic Malignancies: A Case–Control Study

Mycoses, Volume 68, Issue 10, October 2025.
ABSTRACT Background Posaconazole (POS) prophylaxis is recommended for the prevention of invasive mould infections among patients with haematologic cancer and prolonged neutropenia or following allogeneic haematopoietic cell transplantation. Albeit rare, breakthrough invasive mould infections (bIMI) are associated with high mortality rates.
Camille Marchetti, Emmanouil Glampedakis, Jannik Stemler, Luise Hänsel, Sabine Kuster, Ilona Kronig, Katia Boggian, Nina Khanna, Dionysios Neofytos, Oliver A. Cornely, Frederic Lamoth, for the Fungal Infection Network of Switzerland (FUNGINOS), Werner Albrich, Christoph Berger, Anne Bergeron, Sabina Berezowska, Pierre‐Yves Bochud, Katia Boggian, Anna Conen, Stéphane Emonet, Véronique Erard, Christian Garzoni, Daniel Goldenberger, Vladimira Hinic, Cedric Hirzel, Nina Khanna, Malte Kohns, Andreas Kronenberg, Frederic Lamoth, Basile Landis, Oscar Marchetti, Konrad Mühlethaler, Linda Müller, Dionysios Neofytos, Michael Osthoff, Jean‐Luc Pagani, Chantal Quiblier, Ilana Reinhold, Arnaud Riat, Niels Rupp, Dominique Sanglard, Peter Werner Schreiber, Martin Siegemund, Laura Walti   +43 more
wiley   +1 more source

Investigating a novel antifungal drug that inhibits fatty acid desaturation [PDF]

, 2020
Invasive fungal infections represent a group of diseases that are of increasing worldwide concern. This group of diseases is associated with high mortality rates that can be attributed to widespread clinical drug resistance.
Murphy, Sarah
core  

Appearance of Environment‐Linked Azole Resistance in the Aspergillus fumigatus Complex in New Zealand

Mycoses, Volume 68, Issue 8, August 2025.
ABSTRACT Background Until 2020, azole resistance in Aspergillus fumigatus complex isolates in New Zealand was due to cyp51A hot spot mutations. This report details the appearance of environment‐linked tandem repeat (TR)‐related azole resistance genotypes since 2021. Methods Isolates were tested by broth micro‐dilution.
Arthur J. Morris, Wendy P. McKinney, Sally A. Roberts, Sasiharan Sithamparanathan, Zain Chaudhry, Matthew C. Fisher   +5 more
wiley   +1 more source

Investigation of a Lomentospora prolificans case cluster with whole genome sequencing [PDF]

, 2020
Lomentospora prolificans has caused outbreaks in immunocompromised patients. We performed whole genome sequencing (WGS) on 4 L. prolificans isolates from infections occurring during an 8-month period in the haematology unit at Hospital 1., and 2 isolates
Boan, P., Coombs, G.W., Darragh, H., Gardam, D.J., Pang, S., Wright, M.   +5 more
core  

Terapêutica antifúngica: novas moléculas, novas formas de administração e diferentes estratégias para alcançar a toxicidade seletiva [PDF]

, 2021
Nos últimos anos verificou-se um aumento das infeções fúngicas invasivas, devido ao aumento da esperança de vida e do número de doentes imunodeprimidos e ao aparecimento de resistência aos antifúngicos.
Moreira, Marta Alexandra Macedo
core  

The performance and costs of XTT, resazurin, MTS and luciferin as viability dyes in in vitro susceptibility testing of Madurella mycetomatis [PDF]

Background: in vitro susceptibility testing for the non-sporulating fungus Madurella mycetomatis is performed with a hyphal suspension as starting inoculum and a viability dye for endpoint reading.
Eadie, Kimberly, Fahal, Ahmed, Ma, Jingyi, van de Sande, Wendy W. J., Verbon, Annelies   +4 more
core   +4 more sources

Tetflupyrolimet shows selectivity for plant dihydroorotate dehydrogenase over Aspergillus orthologs

Scientific Reports
Shared enzymatic targets between azoles used in agriculture as fungicides and clinical antifungals are hypothesized to have led to the drift of resistant fungal isolates from field to clinic, reducing efficacy of azoles in infectious disease treatment ...
Sang-Ic Kim, Venkataphanikanth Turlapati, Bhavna Agashe, Qun Lu, Sriram Satagopan, James A. Sweigard, Ryan P. Emptage   +6 more
doaj   +1 more source

Antifungal Resistance in Non‐fumigatus Aspergillus Species

Mycoses, Volume 68, Issue 4, April 2025.
ABSTRACT This review provides an in‐depth exploration of antifungal resistance in non‐fumigatus Aspergillus species, mainly focusing on acquired resistance. The available data have been compiled and sometimes re‐analysed. It highlights the increasing prevalence of resistance in non‐fumigatus species belonging to Flavi, Terrei, Nigri, and Nidulantes ...
Elie Djenontin, Rose‐Anne Lavergne, Florent Morio, Eric Dannaoui   +3 more
wiley   +1 more source

The importance of antimicrobial resistance in medical mycology. [PDF]

, 2022
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global health care priority. Some analyses, including the O'Neill report, have predicted that deaths due to drug-resistant bacterial infections may eclipse the total number ...
Berman, J, Bicanic, T, Bromley, M, Chiller, T, Coste, AT, Cuomo, CA, Edgar, K, Gow, NAR, Harrison, TS, Johnson, C, Perlin, DS, Wiederhold, N   +11 more
core   +2 more sources