Results 81 to 90 of about 853 (171)

What is the role of microbial biotechnology and genetic engineering in medicine?

MicrobiologyOpen, Volume 13, Issue 2, April 2024.
Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley   +1 more source

Primary antifungal prophylaxis in hematological malignancies. Updated clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL). [PDF]

At the 10th European Conference on Infections in Leukaemia (ECIL), the guidelines for antifungal prophylaxis in pediatric and adult patients with hematological malignancies (HM) were updated and some changes introduced.
Blennow, O., Busca, A., Cordonnier, C., Lamoth, F., Maertens, J., Maschmeyer, G., Pagano, L., Spadea, M., Xhaard, A.   +8 more
core   +1 more source

FUNGAL INFECTIONS ASSOCIATED WITH COVID-19 [PDF]

, 2021
To study fungal infections such as Mucormycosis, Aspergillosis, Candidiasis, Cryptococcosis associated with Covid-19. A detailed study was done with the information gathered from the articles in specified databases, online sources, and online published ...
AGARWAL, RICHA, ASIJA, RAJESH, SHARMA, ANTA, TANWAR, SONIKA   +3 more
core   +1 more source

New and emerging options for management of invasive fungal diseases in paediatric patients

Mycoses, Volume 67, Issue 1, January 2024.
Abstract Invasive fungal diseases (IFDs) play an important role in the supportive care of paediatric patients with acute leukaemia and those undergoing allogeneic haematopoietic cell transplantation, and they are associated with significantly decreased overall survival rates in affected individuals.
Andreas H. Groll, Katharina Körholz, Malcolm Holterhus, Thomas Lehrnbecher   +3 more
wiley   +1 more source

Knowledge Mapping of Aspergillus‐Related Research in Respiratory Medicine: A Bibliometric Analysis Based on English‐Language Articles Spanning 1975 to 2022

Canadian Respiratory Journal, Volume 2024, Issue 1, 2024.
Background: Aspergillus has become the second most common causative agent of invasive fungal infections and is the leading cause of death from fungal infections. Methods: English‐language publications ranging from 1975 to 2022 collected from the Web of Science Core Collection database were analyzed visually using VOSviewer, R package Bibliometrix ...
Fan Jiang, Xuemei Li, Qing Qiao, Ge Zhang, Yanmei Zhang, Lin Su, Alexandru Corlateanu   +6 more
wiley   +1 more source

Olorofim for the treatment of invasive fungal diseases in patients with few or no therapeutic options: a single-arm, open-label, phase 2b study

BackgroundOnly a small number of antifungal therapies for invasive fungal disease (IFD) are currently available, and many pathogens are resistant to one or more of these therapies. Olorofim, the first orotomide antifungal agent to be developed, is active
Aguado, Jose Maria, Alexander, Barbara D, Aoun, Mickael, Bazaz, Rohit, Bruns, Anke H W, Brüggemann, Roger J, Chayakulkeeree, Methee, Chen, Sharon C A, Cornelissen, Karen, Cornely, Oliver A, Dane, Aaron, Donovan, Fariba M, Fitton, Lesley, Fortún, Jesus, Georgala, Aspasia, Hammond, Sarah P, Heath, Christopher H, Hoenigl, Martin, Holland, Steven M., Johnson, Royce, Koehler, Philipp, Maertens, Johan A, Mehra, Varun, Mehta, Sanjay R, Miceli, Marisa H, Morrissey, C Orla, Moussa, Mohamed, Nguyen, M Hong, Ostrosky-Zeichner, Luis, Paterson, David L., Patterson, Thomas F, Plate, Markus, Rahav, Galia, Rex, John H., Richardson, Riina, Rijnders, Bart, Ross, Geoffrey G, Schaenman, Joanna, Schwartz, Stefan, Shoham, Shmuel, Sikka, Monica K, Slavin, Monica A, Sole, Amparo, Spec, Andrej, Thompson, George R, Uspenskaya, Olga, Vazquez, Jose A, Veerdonk, Frank L. van de, Verweij, Paul E, Walsh, Stephen R, Walsh, Thomas J, White, P Lewis, Yehudai-Ofir, Dana, Zinzi, Daniela   +53 more
core   +2 more sources

Olorofim Susceptibility Testing of 1,423 Danish Mold Isolates Obtained in 2018-2019 Confirms Uniform and Broad-Spectrum Activity

Antimicrobial Agents and Chemotherapy, 2020
Olorofim is a novel antifungal drug in phase 2 trials. It has shown promising in vitro activity against various molds, except for Mucorales. Initially, we observed a broad range of EUCAST MICs for Aspergillus fumigatus .
Karen Marie Thyssen Astvad, Karin Meinike Jørgensen, Rasmus Krøger Hare, Raluca Datcu, Maiken Cavling Arendrup   +4 more
openaire   +4 more sources

Fusarium species,Scedosporium species, and Lomentospora prolificans: A systematic review to inform the World Health Organization priority list of fungal pathogens [PDF]

Recognizing the growing global burden of fungal infections, the World Health Organization established a process to develop a priority list of fungal pathogens (FPPL).
Al-Nuseirat, Adi, Alastruey-Izquierdo, Ana, Beyer, Peter, Bupha-Intr, Olivia, Cassini, Alessandro, Chiller, Tom M, Colombo, Arnaldo, Dao, Aiken, Denning, David W, Forastiero, Agustina, Fusire, Terence, Garnham, Katherine, Halliday, Catriona L, Hamers, Raph L, Kim, Hannah Yejin, Marinelli, Tina, Morris, Arthur J, Nucci, Marcio, Oladele, Rita, Perfect, John, Ramon-Pardo, Pilar, Rickerts, Volker, Sorrell, Tania C, Wahyuningsih, Retno   +23 more
core   +5 more sources

Endocarditis caused by Scopulariopsis brevicaulis with disseminated emboli and multiple vascular aneurysms: A case report and literature review

IDCases
Background: Scopulariopsis brevicaulis, a saprophytic fungus often associated with onychomycosis, has seldom been reported to cause deep-tissue infections in immunocompromised patients.
Kieffer Korvin, Myriam Chiarruzi, Aurélie Martin, Clara Gromoff, Vlad Ciobotaru, Milène Sasso, Marie-Clothilde Brunet, Romaric Larcher, Paul Loubet   +8 more
doaj   +1 more source

Multiresistant Fusarium Pathogens on Plants and Humans: Solutions in (from) the Antifungal Pipeline?

Infection and Drug Resistance, 2019
Abdullah MS Al-Hatmi,1–3 G Sybren de Hoog,2,3 Jacques F Meis3,4 1Ministry of Health, Directorate General of Health Services, Ibri, Oman; 2Westerdijk Fungal Biodiversity Institute, Utrecht, the Netherlands; 3Centre of Expertise in Mycology Radboud ...
Al-Hatmi AMS, de Hoog GS, Meis JF
doaj