Results 1 to 10 of about 121 (98)

The Role of Bacteriophages in the Gut Microbiota: Implications for Human Health [PDF]

Pharmaceutics, 2023
Bacteriophages (phages) are nano-sized viruses characterized by their inherent ability to live off bacteria. They utilize diverse mechanisms to absorb and gain entry into the bacterial cell wall via the release of viral genetic material, which uses the ...
Stephen C. Emencheta, Chinasa V. Olovo, Osita C. Eze, Chisom F. Kalu, Dinebari P. Berebon, Ebele B. Onuigbo, Marta M. D. C. Vila, Victor M. Balcão, Anthony A. Attama   +8 more
doaj   +2 more sources

Microbial ecology and evolution is key to pandemics: using the coronavirus model to mitigate future public health challenges [PDF]

Heliyon, 2022
Pandemics are global challenges that lead to total disruption of human activities. From the inception of human existence, all pandemics have resulted in loss of human lives.
Emmanuel Sunday Okeke, Chinasa Valerie Olovo, Ndidi Ethel Nkwoemeka, Charles Obinwanne Okoye, Chidiebele Emmanuel Ikechukwu Nwankwo, Chisom Joshua Onu   +5 more
doaj   +2 more sources

Cellular and molecular mediators of lymphangiogenesis in inflammatory bowel disease [PDF]

Journal of Translational Medicine, 2021
Background Recent studies reporting the intricate crosstalk between cellular and molecular mediators and the lymphatic endothelium in the development of inflammatory bowel diseases (IBD) suggest altered inflammatory cell drainage and lymphatic ...
Dickson Kofi Wiredu Ocansey, Bing Pei, Xinwei Xu, Lu Zhang, Chinasa Valerie Olovo, Fei Mao   +5 more
doaj   +2 more sources

The deuce-ace of Lassa Fever, Ebola virus disease and COVID-19 simultaneous infections and epidemics in West Africa: clinical and public health implications [PDF]

Tropical Medicine and Health, 2021
Globally, the prevailing COVID-19 pandemic has caused unprecedented clinical and public health concerns with increasing morbidity and mortality. Unfortunately, the burden of COVID-19 in Africa has been further exacerbated by the simultaneous epidemics of
Nnabueze Darlington Nnaji, Helen Onyeaka, Rine Christopher Reuben, Olivier Uwishema, Chinasa Valerie Olovo, Amarachukwu Anyogu   +5 more
doaj   +2 more sources

The diagnostic and prognostic potential of gut bacteria in inflammatory bowel disease [PDF]

Gut Microbes, 2023
The gut microbiome serves as a signaling hub that integrates environmental inputs with genetic and immune signals to influence the host’s metabolism and immunity.
Dickson Kofi Wiredu Ocansey, Sanhua Hang, Xinyi Yuan, Hua Qian, Mengjiao Zhou, Chinasa Valerie Olovo, Xu Zhang, Fei Mao   +7 more
doaj   +2 more sources

Towards Improved Use of Vaccination in the Control of Infectious Bronchitis and Newcastle Disease in Poultry: Understanding the Immunological Mechanisms [PDF]

Vaccines, 2021
Infectious bronchitis (IB) and Newcastle disease (ND) are two important diseases of poultry and have remained a threat to the development of the poultry industry in many parts of the world.
Anthony C. Ike, Chukwuebuka M. Ononugbo, Okechukwu J. Obi, Chisom J. Onu, Chinasa V. Olovo, Sophia O. Muo, Okoro S. Chukwu, Eleazar E. Reward, Odinakachukwu P. Omeke   +8 more
doaj   +2 more sources

The influence of gut microbiota on the gut-brain-kidney axis and its implications for chronic kidney disease [PDF]

Frontiers in Microbiology
The gut-brain-kidney axis represents a dynamic interplay among the gut microbiota, renal function, and neurological processes, emerging as a critical factor in chronic kidney disease (CKD) pathophysiology. This paper reviews recent data on the mechanisms
Jue Zhu, Yutong Fu, Yutong Fu, Chinasa Valerie Olovo, Chinasa Valerie Olovo, Jianguo Xu, Qian Wu, Wei Wei, Ke Jiang, Ke Jiang, Xueming Zheng, Xueming Zheng   +11 more
doaj   +2 more sources

Bacterial membrane vesicles in the pathogenesis and treatment of inflammatory bowel disease [PDF]

Gut Microbes
Inflammatory bowel disease (IBD) is a chronic and debilitating condition of relapsing and remitting inflammation in the gastrointestinal tract. Conventional therapeutic approaches for IBD have shown limited efficacy and detrimental side effects, leading ...
Chinasa Valerie Olovo, Dickson Kofi Wiredu Ocansey, Ying Ji, Xinxiang Huang, Min Xu   +4 more
doaj   +2 more sources

The potential immunological mechanisms of gut microbiota dysbiosis caused by antibiotics exacerbate the lethality of influenza viruses [PDF]

Gut Microbes
Background Antibiotics are not recommended to treat influenza A virus (IAV). However, antibiotic misuse for IAV persists worldwide. How to scientifically use antibiotics for IAV-infected patients remains a considerable challenge.Results Here, we ...
Jianing Zhu, Zihang Huang, Ying Lin, Jie Zhu, Rui Min, Zibo Wan, Yuting Chen, Jianwen Zhu, Li Xing, Sheng Li, Chinasa Valerie Olovo, Xiaoquan Wang, Guocai Li, Pinghu Zhang   +13 more
doaj   +2 more sources

Chemical Toxicants Used for Food Preservation in Africa. Is it a Case of Ignorance or Food Fraud? A Review [PDF]

Health Science Reports
Background and Aims This review examined the use of chemical preservatives in food preservation and the food fraud risks associated with its misuse in Africa.
Nnabueze Darlington Nnaji, Helen Onyeaka, Kingsley Tochukwu Ughamba, Chukwuebuka Maxwell Ononugbo, Chinasa Valerie Olovo, Ifeanyi Michael Mazi   +5 more
doaj   +2 more sources