Results 161 to 170 of about 48,481 (265)
Akkermansia muciniphila and Its Bioactive Derivatives: Emerging Regulators of Healthy Aging
Aging Cell, Volume 25, Issue 9, September 2026.The beneficial gut bacterium Akkermansia muciniphila (AKK) declines with age but is enriched in healthy centenarians. Supplementation of AKK extends healthspan and alleviates age‐related decline through direct host–microbe interactions and its bioactive derivatives, which collectively enhance gut barrier integrity, restore metabolic homeostasis ...Ting Zhang, Jinyuan Niu, Xiaoyu Hu, Zhiang Hu, Yuan Gao, Jialiang Liu, Ning Chen, Yaomin Hu +7 morewiley +1 more sourceFeatures OF Anatomy OF the Greater Omentum
The article has studied in detail the macro and microscopic anatomy of the greater omentum of a person. Variants, morphological, histotopographic features and ligament apparatus of the greater omentum are indicated.Raxmatovich, N. J. (Nurov), qizi, A. M. (Ahmadova) +1 morecore Detection and treatment of peritoneal metastases in colon cancer: COLOPEC trial compared to routine practice
Colorectal Disease, Volume 28, Issue 9, September 2026.Abstract Aim
The randomized COLOPEC trial demonstrated no benefit of adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in preventing peritoneal metastases in locally advanced colon cancer. Because all patients underwent a diagnostic laparoscopy at 18 months, the study lacked a true control arm, leaving the effect of early detection and ...Iris Hochstenbach, Julie J. M. Hamm, Eva Rademaker, Arend G. J. Aalbers, Djamila Boerma, Wilhelmina M. U. van Grevenstein, Patrick H. J. Hemmer, Ignace H. J. T. De Hingh, Niels F. M. Kok, Jurriaan B. Tuynman, Eva V. E. Madsen, Johannes H. W. de Wilt, Esther C. J. Consten, Henderik L. van Westreenen, Pieter J. Tanis, on behalf of the COLOPEC Collaborators Group, Dutch Snapshot Research Group and Dutch Complex Colon Cancer Initiative, Caroline S. Andeweg, Vivian P. Bastiaenen, Willem A. Bemelman, Jarmila D.W. van der Bilt, Johanne Bloemen, Frank C. den Boer, Daan ten Bokkel Huinink, Cancer Clinic, Alexandra R.M. Brandt‐Kerkhof, Andre J.A. Bremers, Walter J.A. Brokelman, Huib A. Cense, Geert‐Jan Creemers, Johannes Crezee, Rogier M.P.H. Crolla, Jan‐Willem T. Dekker, Jennifer Demelinne, Marc J. van Det, Ziekehuisgroep Twente, Karin K. van Diepen, Marjolein Diepeveen, Gastrointestinal Surgery, Marcel G.W. Dijkgraaf, Eino B. van Duyn, Medisch Spectrum Twente, Esther D. van den Ende, Ziekehuisgroep Twente, Pauline Evers, Hans F.J. Fabry, Floris T.J. Ferenschild, Maashospital Pantein, Sebastiaan Festen, Onze Lieve Vrouwen Gasthuis, Anna A.W. van Geloven, Erwin van der Harst, Jeroen Heemskerk, Joost T. Heikens, Daniel A. Hess, Bas Inberg, Streekziekenhuis Koningin Beatrix, Jan Jansen, Charlotte E.L. Klaver, Frank W.H. Kloppenberg, Treant Zorggroep, Thomas J.M. Kootstra, R. T. J. Kortekaas, Maartje Los, H. C. J. van der Mijle, Linda Mol, Gijsbert D. Musters, Peter A. Neijenhuis, Simon W. Nienhuijs, Loes van den Nieuwenhof, Koen C.M.J. Peeters, Sebastiaan W. Polle, Jolien Pon, Pieter Poortman, Cornelis J.A. Punt, Sandra A. Radema, Bert van Ramshorst, Philip R. de Reuver, Koen P. Rovers, Roderick F. Schmitz, Lotte Schoonderwoerd, Nina Sluiter, Dirkje W. Sommeijer, Eric Sonneveld, T. C. van Sprundel, Sanne C. Veltkamp, Maarten Vermaas, Victor J. Verwaal, Emma Wassenaar, Johannes A. Wegdam, Marinke Westerterp, Marinus J. Wiezer, Daniel D. Wisselink, Fennie Wit, Arjen J. Witkamp, Karlijn van Woensdregt, Edwin S. van der Zaag, David D.E. Zimmerman, Mandy Zournas, Annette van Zweeden, D. C. Van der Aa, S. M. Van Aalten, I. Aanen, F. J. Amelung, Den Bosch, P. Van Amstel, E. Ancion, J. J. Atema, T. S. Aukema, V. Baart, E. Z. Barsom, V. P. Bastiaenen, T. Bazuin, M. A. J. Becker, V. M. Belvroy, R. H. A. Berndsen, B. Biersteker, J. D. W. Van der Bilt, J. G. Bloemen, S. Bluiminck, F. C. Den Boer, E. G. Boerma, M. C. Boonstra, W. A. A. Borstlap, L. A. Brugts, J. W. A. Burger, T. A. Burghgraef, S. M. M. De Castro, M. Cleveringa, R. J. S. Coelen, A. Demirkiran, E. Dijkema, S. Dijkink, S. A. Dingemans, L. Van Dullemen, E. B. Van Duyn, A. J. Eleveld, H. A. Galema, E. G. M. Van Geffen, R. T. J. Geitenbeek, A. A. W. Van Geloven, A. H. C. Gielen, C. A. Gispen, M. J. P. M. Govaert, V. P. Groot, B. A. Grotenhuis, A. A. J. Grüter, S. F. Hardon, A. G. Den Hartog, K. Havenga, J. A. G. Van der Heijden, F. Heilijgers, T. B. M. Van den Heuvel, R. S. Hijmans, J. Van Hilst, J. C. Hol, S. Janki, A. C. H. M. Jongen, I. Kappers, S. Karhof, B. A. J. Kertzman, M. M. Kieboom, N. Koemans, J. L. M. Konsten, W. H. Kopp, O. W. Kranenburg, P. Krielen, A. Kumas, M. Kusters, D. P. V. Lambrichts, B. Lamme, G. L. Van Leeuwen, E. W. Lockhorst, H. Lutfi, S. Malm, H. T. J. Mantel, G. A. Martini, P. Meijer, J. Melenhorst, D. M. Mens, MC Erasmus, M. J. H. Metman, L. C. F. De Nes, L. R. Moolenaar, J. A. Nieuwstraten, J. Nonner, S. E. Van Oostendorp, S. J. Oosterling, C. M. W. Pesch, C. M. L. Peters, M. W. H. Philipsen, W. Y. Van der Plas, M. M. Poelman, F. Polat, A. E. Posma‐Bouman, B. B. Pultrum, J. M. Van Rees, W. P. Reinders, P. R. De Reuver, M. C. Richir, T. W. H. Rijnhout, M. M. Romeijn, D. Roorda, C. C. Van Rossem, J. Rothbarth, M. Ruig, H. G. Sahin, I. Said, R. A. Schasfoort, J. Scholten, P. M. E. Schuivens, D. Schweitzer, C. Sietses, M. Sietzema, G. D. Slooter, N. Smakman, B. P. Smalbroek, E. J. Spillenaar Bilgen, E. J. A. Steller, T. F. Stoop, M. Straver, S. K. Stuart, A. Suntharan, A. K. Talsma, K. Trumpi, J. Veenhuizen, A. W. H. Van de Ven, E. G. G. Verdaasdonk, P. M. Verheijen, A. Villerius‐Meijer, M. Vissers, E. L. K. Voogt, R. P. H. De Vries, S. T. Van Vugt, D. D. De Waard, T. R. Wagner, A. K. Warps, R. H. A. Welling, M. Westerterp, J. K. Wiggers, A. R. Wijsmuller, C. D. M. Witjes, B. Zamaray, N. Van Zenden, S. J. M. Zomer, E. S. Zwanenburg, E. S. Zwart, S. L. M. Zwetsloot, M. J. Lahaye, P. D. Siersema, P. Snaebjornsson +250 morewiley +1 more sourceUnveiling the molecular profile of adenosquamous gallbladder carcinoma: characterization of a Caucasian cohort
Histopathology, Volume 89, Issue 3, Page 442-455, September 2026.GBASCs are MMRp tumours, exhibiting minimal HER2 overexpression and elevated PD‐L1 expression compared to adenocarcinomas. Especially in metastatic and TP53‐wild type tumours, GBASCs can express CLDN18, albeit limited to the glandular component. Their genomic profile resembles that of adenocarcinomas with an enrichment in alterations on PIK3CA, PTEN ...Jessica Gasparello, Valentina Angerilli, Mario Domenico Rizzato, Edoardo Maffii, Carlotta Ceccon, Matilde Callegarin, Marianna Sabbadin, Monia Niero, Luisa Toffolatti, Francesca Bergamo, Paola Parente, Luca Mastracci, Federica Grillo, Alessandro Vanoli, Paola Mattiolo, Claudio Luchini, Angelo Paolo Dei Tos, Umberto Cillo, Giacomo Zanus, Sara Lonardi, Matteo Fassan +20 morewiley +1 more sourceCurrent and Future Perspectives on Adipo‐Oncology: Roles of Adipocytes in Local and Systemic Tumor Regulation
Pathology International, Volume 76, Issue 9, September 2026.Adipocytes regulate tumor development and progression through both local and systemic mechanisms. Local regulation involves cancer‐associated adipocytes, paracrine signaling, lipid transfer, and modulation of stromal and immune cells, whereas adipokines, inflammatory cytokines, extracellular vesicles, and lipid transfer mediate systemic regulation ...Shinya Satowiley +1 more sourcePrimary torsion of the omentum
, 1997 0Primary Torsion of the Omentum Primary omental torsion is a rare surgical entity and less than 100 case has been reported. It usually mimicks other acute abdominal pathologies.core Primary Bronchial Hybrid Low‐Grade Fibromyxoid Sarcoma/Sclerosing Epithelioid Fibrosarcoma With EWSR1::CREB3L1 Fusion: Diagnostic Insights From a Challenging Case in the Respiratory Tract
Pathology International, Volume 76, Issue 9, September 2026.We report a primary bronchial hybrid low‐grade fibromyxoid sarcoma/sclerosing epithelioid fibrosarcoma (LGFMS/SEF) characterized by histological, immunohistochemical, and molecular findings, including detection of an EWSR1::CREB3L1 fusion by comprehensive genomic profiling.Hiroko Ikeda, Seiichi Kakegawa, Daisuke Saito, Keita Kinoshita, Ayumi Ito, Keishi Mizuguchi, Seiji Yano, Tomohiro Kobayashi, Satoshi Kobayashi, Akihiro Nishiyama, Shinji Takeuchi, Isao Matsumoto +11 morewiley +1 more source