Results 171 to 180 of about 30,804 (255)

Synergistic Potential of Repurposing non-β-lactam Compounds as Class A serine β-lactamases Inhibitor: Insights from MolecularDocking, Molecular Dynamics Simulations and Antimicrobial Potentiation. [PDF]

Sci Rep
Abdalla MS, Dutta S, Sulieman MO, Jaber AA, Noorelhuda MO, Elkhidir OF, Sardar S, Hajhamed NM, Awad TA, Mustafa SA, Lee SG, Aldin NAM.   +11 more
europepmc   +1 more source

The Metabolism and Pharmacokinetics of Omeprazole in Relation to CYP2C19 [PDF]

Omeprazole is one of the most widely used proton pump inhibitors for the treatment of gastric acid-related disorders. Omeprazole is completely metabolized, predominantly to 5-hydroxyomeprazole catalyzed by CYP2C19, which shows genetically determined ...
宇野, 司, Uno, Tsukasa
core  

Successful use of haemoperfusion therapy in an adult horse with hepatic encephalopathy and cholangiohepatitis

Equine Veterinary Education, Volume 38, Issue 6, Page e307-e314, June 2026.
Summary A 4‐year‐old, 520 kg, American Quarter Horse broodmare, approximately 90 days in foal, was presented to Texas A&M University Teaching Hospital for suspected liver disease. Based on clinicopathological values and hepatic abnormalities noted ultrasonographically, the mare was presumptively diagnosed with cholangiohepatitis.
A. C. Trimble, S. H. White‐Springer, S. Alpini, E. Rumfola, A. N. DiSilvestro, Y. Ueda, K. Hobbs   +6 more
wiley   +1 more source

Effects of Cedirogant on the Pharmacokinetics of Sensitive Cytochrome P450 Probe Substrates. [PDF]

Clin Pharmacol Drug Dev
D'Cunha R, Qian Y, Hao S, Eccleston J, Levy GF, Gannu S, Rizzo DG, Liu W, Mohamed MF.   +8 more
europepmc   +1 more source

‘We're the Eyes and Ears… out There’: A Qualitative Exploration of the Perceptions and Experiences of Polypharmacy Amongst Home Care Providers

Health Expectations, Volume 29, Issue 3, June 2026.
ABSTRACT Introduction Polypharmacy is often managed at home by older people and those involved in their day‐to‐day care. Home care workers are well placed to play a crucial role, but there is little research in this setting. This study aimed to explore experiences and perceptions of polypharmacy amongst providers of home care.
Anum Iqbal, Liam Mullen, Adam Todd, Barbara Hanratty   +3 more
wiley   +1 more source

Burn Wound Infections With Staphylococcus aureus: Clinical Characteristics and Risk Factors for Methicillin‐Resistant Strains

International Wound Journal, Volume 23, Issue 6, June 2026.
ABSTRACT This study aimed to systematically delineate the clinical characteristics and identify the key risk factors associated with methicillin‐resistant Staphylococcus aureus (MRSA) infections in burn patients, thereby informing targeted preventive measures and therapeutic strategies.
Xiaolan Hong, Shaobo Zhou, Qinghua Cai, Yuanyuan Cai, Zhaohong Chen, Wanting Zhao, Yongjian Ye, Xubo Dai   +7 more
wiley   +1 more source

Including Vonoprazan With PPIs Challenges the Drug-Interaction Hypothesis. [PDF]

JACC Asia
Shamsulddin AB.
europepmc   +1 more source

Rationalizing Proton Pump Inhibitor Use: Southeast Asia Consensus Recommendations

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1685-1700, June 2026.
ABSTRACT Background and Aim Proton pump inhibitors (PPIs) are integral to managing many gastrointestinal conditions. However, the prevalent inappropriate PPI prescription across Southeast Asia (SEA) is concerning. Given the absence of locally tailored recommendations to inform clinical practice, this consensus document aims to provide recommendations ...
Somchai Leelakusolvong, Tju Siang Chua, Duc Trong Quach, Andrew Ming‐Liang Ong, Ari Fahrial Syam, Augusto Jose G. Galang, Wee Kooi Cheah, Hang Viet Dao, Jose D. Sollano, Kalwinder Singh Khaira, Phuripong Kijdamrongthum, Rahela Ambaras Khan, Sakkarin Chirapongsathorn, Yeong Yeh Lee   +13 more
wiley   +1 more source

Lack of gastric acidification reduces postprandial energy expenditure and protein digestion but not growth in Astyanax mexicanus. [PDF]

J Exp Biol
Ferreira PG, Flávio H, Wilson JM.
europepmc   +1 more source

Poliprotect in the PPI Deprescription Phase of Endoscopy‐Negative Heartburn and Epigastric Pain Syndrome Patients: An RCT Post Hoc Analysis

Neurogastroenterology &Motility, Volume 38, Issue 6, June 2026.
Deprescribing PPIs is often difficult because of symptom recurrence and rebound acid hypersecretion, and evidence supporting effective deprescribing strategies is scarce. This post hoc analysis shows that on‐demand Poliprotect is a safe and potentially effective strategy to maintain or improve symptom control in non‐erosive reflux and epigastric pain ...
Enrico Stefano Corazziari, Antonio Gasbarrini, Lucia D'Alba, Valeria D'Ovidio, Oliviero Riggio, Sandro Passaretti, Bruno Annibale, Michele Cicala, Alessandro Repici, Gabrio Bassotti, Carolina Ciacci, Antonio Di Sabatino, Matteo Neri, Maria Consiglia Bragazzi, Emanuela Ribichini, Paola Iovino, Danilo Badiali   +16 more
wiley   +1 more source