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APIK Journal of Internal Medicine, 2022 Emerging infectious diseases are now a concern worldwide and can evolve into a global health-care crisis or pandemic. Identification of the Omicron variant (B.1.1.529) of severe acute respiratory syndrome-2 (SARS-CoV-2) which is considered a variant of concern has added fuel to the eternal flame of the global COVID-19 pandemic.
Vasantha Kamath, Deepthi Reddy
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Nature Reviews Immunology, 2022 Three recent preprints investigate the entry route of SARS-CoV-2 Omicron variant into host cells and its cellular and host tropism.
Luisanna Pia, Sarah Rowland-Jones
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Molecular Medicine, 2022 Background The use of doxorubicin is associated with an increased risk of acute and long-term cardiomyopathy. Despite the constantly growing number of cancer survivors, little is known about the transcriptional mechanisms which progress in the time ...
Justyna Totoń-Żurańska +12 more
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Variants influencing age at diagnosis of HNF1A-MODY
Molecular Medicine, 2022 Background HNF1A-MODY is a monogenic form of diabetes caused by variants in the HNF1A gene. Different HNF1A variants are associated with differences in age of disease onset, but other factors are postulated to influence this trait.
Agnieszka H. Ludwig-Słomczyńska +15 more
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Low Expression of miR-375 and miR-190b Differentiates Grade 3 Patients with Endometrial Cancer
Biomolecules, 2021 Endometrial cancer (EC) is treated according to the stage and prognostic risk factors. Most EC patients are in the early stages and they are treated surgically.
Miłosz Pietrus +5 more
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Molecular Medicine, 2021 Background Clinical data suggest that BMI and gestational weight gain (GWG) are strongly interconnected phenotypes; however, the genetic basis of the latter is rather unclear. Here we aim to find genes and genetic variants which influence BMI and/or GWG.
Agnieszka H. Ludwig-Słomczyńska +10 more
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Mitochondrial GWAS and association of nuclear – mitochondrial epistasis with BMI in T1DM patients
BMC Medical Genomics, 2020 Background BMI is a strong indicator of complications from type I diabetes, especially under intensive treatment. Methods We have genotyped 435 type 1 diabetics using Illumina Infinium Omni Express Exome-8 v1.4 arrays and performed mitoGWAS on BMI.
Agnieszka H. Ludwig-Słomczyńska +11 more
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PLoS ONE, 2023 BackgroundTo compare the intrinsic virulence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant with the delta variant in hospitalized adults with coronavirus disease 2019 (COVID-19).MethodsAll adults hospitalized in the ...
COVID-19 Omicron Delta study group
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Health and participation in the Lolland-Falster Health Study: a cohort study
BMJ Public Health, 2023 Background Lolland-Falster is the area of Denmark with highest mortality. However, clinical measurements from a population-based health survey showed prevalence of disease indicators similar to those in the rest of Denmark. The study aimed to disentangle
George Maria Napolitano +2 more
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New Scientist, 2021 The discovery of a highly mutated coronavirus variant in South Africa has triggered a global scramble, reports Adam Vaughan.
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