Results 51 to 60 of about 407,505 (399)

Art‐omics: multi‐omics meet archaeology and art conservation [PDF]

Microbial Biotechnology, 2019
Summary Multi‐omics can informally be described as the combined use of high‐throughput techniques allowing the characterization of complete microbial communities by the sequencing/identification of total pools of biomolecules including DNA , proteins or metabolites.
Cristina Vilanova, Manuel Porcar
openaire   +4 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Effects of the turn-back primer on intermediate product generation in isothermal DNA amplification

BioTechniques, 2010
In DNA amplification, the initial step of copying a target sequence from the template DNA, or the so-called intermediate product generation step, is very important.
Yuki Tanaka, Yasumasa Kimura, Yasumasa Mitani, Yuki Kawai, Alexander Lezhava, Shohei Noma, Michihira Tagami, Jun Kawai, Yoshihide Hayashizaki, Kengo Usui   +9 more
doaj   +1 more source

Criteria for the use of omics-based predictors in clinical trials. [PDF]

, 2013
The US National Cancer Institute (NCI), in collaboration with scientists representing multiple areas of expertise relevant to 'omics'-based test development, has developed a checklist of criteria that can be used to determine the readiness of omics-based
A Dupuy, AM Molinaro, B Freidlin, Barbara A. Conley, David A. Eberhard, Deborah J. Shuman, HM Moore, J Subramanian, James H. Doroshow, James V. Tricoli, Jeremy M. G. Taylor, Jill P. Mesirov, JT Leek, Kelly Y. Kim, KK Dobbin, L Shi, Lisa M. McShane, LM McShane, Margaret M. Cavenagh, Mei-Yin C. Polley, P. Mickey Williams, R Simon, Richard M. Simon, RM Simon, Tracy G. Lively, William L. Bigbee   +25 more
core   +2 more sources

WebGestalt 2024: faster gene set analysis and new support for metabolomics and multi-omics

Nucleic Acids Research
Enrichment analysis, crucial for interpreting genomic, transcriptomic, and proteomic data, is expanding into metabolomics. Furthermore, there is a rising demand for integrated enrichment analysis that combines data from different studies and omics ...
John M Elizarraras, Yuxing Liao, Zhiao Shi, Qian Zhu, Alexander R. Pico, Bing Zhang   +5 more
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Development of FuGO: An ontology for functional genomics investigations [PDF]

, 2006
The development of the Functional Genomics Investigation Ontology (FuGO) is a collaborative, international effort that will provide a resource for annotating functional genomics investigations, including the study design, protocols and instrumentation ...
Brinkman, Ryan R., Causton, Helen C., Fan, Liju, Field, Dawn, Fostel, Jennifer, Fragoso, Gilberto, Gray, Tanya, Heiskana, Mervi, Hernandez-Boussard, Tina, Smith, Barry, Whetzel, Patricia L.   +10 more
core  

Omics assisted N-terminal proteoform and protein expression profiling on methionine aminopeptidase 1 (MetAP1) deletion [PDF]

, 2018
Excision of the N-terminal initiator methionine (iMet) residue from nascent peptide chains is an essential and omnipresent protein modification carried out by methionine aminopeptidases (MetAPs) that accounts for a major source of N-terminal proteoform ...
Fijalkowska, Daria, Jonckheere, Veronique, Van Damme, Petra   +2 more
core   +1 more source

Wekemo Bioincloud: A user‐friendly platform for meta‐omics data analyses

iMeta
The increasing application of meta‐omics approaches to investigate the structure, function, and intercellular interactions of microbial communities has led to a surge in available data.
Yunyun Gao, Guoxing Zhang, Shunyao Jiang, Yong-Xin Liu   +3 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source