Results 11 to 20 of about 71,620 (260)
Integrative Multi-Omics in Biomedical Research [PDF]
Biomolecules, 2021 Genome technologies have revolutionized biomedicine, but the complexity of biological systems cannot be explained by genomics alone [...]
Hill, Michelle M., Gerner, Christopher
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Techniques for integrating -omics data [PDF]
Bioinformation, 2009 The challenge for -omics research is to tackle the problem of fragmentation of knowledge by integrating several sources of heterogeneous information into a coherent entity. It is widely recognized that successful data integration is one of the keys to improve productivity for stored data.
Siva Prasad, Akula +4 more
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Integrative omics for health and disease [PDF]
Nature Reviews Genetics, 2018 Advances in omics technologies - such as genomics, transcriptomics, proteomics and metabolomics - have begun to enable personalized medicine at an extraordinarily detailed molecular level. Individually, these technologies have contributed medical advances that have begun to enter clinical practice.
Konrad J, Karczewski, Michael P, Snyder
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Graph-Based Integration of Histone Modification Profiles
Mathematics, 2022 In this work, we introduce a similarity-network-based approach to explore the role of interacting single-cell histone modification signals in haematopoiesis—the process of differentiation of blood cells.
Federica Baccini +2 more
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Omics and Multi-Omics in IBD: No Integration, No Breakthroughs
International Journal of Molecular Sciences, 2023 The recent advent of sophisticated technologies like sequencing and mass spectroscopy platforms combined with artificial intelligence-powered analytic tools has initiated a new era of “big data” research in various complex diseases of still-undetermined cause and mechanisms.
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MathIOmica: An Integrative Platform for Dynamic Omics [PDF]
Scientific Reports, 2016 Abstract Multiple omics data are rapidly becoming available, necessitating the use of new methods to integrate different technologies and interpret the results arising from multimodal assaying. The MathIOmica package for Mathematica provides one of the first extensive ...
Mias, George I. +5 more
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Transcriptomic and Metabolomic Response to High Light in the Charophyte Alga Klebsormidium nitens
Frontiers in Plant Science, 2022 The characterization of the molecular mechanisms, such as high light irradiance resistance, that allowed plant terrestralization is a cornerstone in evolutionary studies since the conquest of land by plants played a pivotal role in life evolution on ...
Emma Serrano-Pérez +9 more
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Editorial: Multi-omic data integration [PDF]
Frontiers in Cell and Developmental Biology, 2015 As researchers involved in molecular biology, we are witnessing tremendous paradigm changes in a time frame that becomes shorter and shorter. The epoch-making notion, originally put forward by the central dogma of biology (Crick, 1970), that there is a unidirectional process and a privileged level (genetic) of causality at which biological functions ...
Christine eNardini +3 more
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Multi-modal intermediate integrative methods in neuropsychiatric disorders: A review
Computational and Structural Biotechnology Journal, 2022 The etiology of neuropsychiatric disorders involves complex biological processes at different omics layers, such as genomics, transcriptomics, epigenetics, proteomics, and metabolomics.
Yanlin Wang +5 more
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Omics Fusion – A Platform for Integrative Analysis of Omics Data
Journal of Integrative Bioinformatics, 2016 Summary We present Omics Fusion, a new web-based platform for integrative analysis of omics data. Omics Fusion provides a collection of new and established tools and visualization methods to support researchers in exploring omics data, validating results or understanding how to adjust experiments in order to make new discoveries.
Brink, Benedikt +4 more
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