Time‐Efficient and Informatic‐Skill‐Light Gap‐Filling for Telomere‐to‐Telomere Genome Assembly
The paper introduces a novel auxiliary software toolbox GapSuite, consisting of two tools Gap‐Aid and Gap‐Graph, which guides users to fill gaps in chromosome‐level genome assembly using sequence‐extension‐based and assembly‐graph‐based strategies. The two tools enable users with limited informatics expertise to efficiently complete gap‐filling on ...
Dong Xu +8 more
wiley +1 more source
GAUDI: interpretable multi-omics integration with UMAP embeddings and density-based clustering. [PDF]
Castellano-Escuder P +3 more
europepmc +1 more source
3D integrated spatial OMICS data
Spatial OMICS data sets integrated in 3D models of whole developmental ...
openaire +1 more source
Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D
CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley +1 more source
A review on multi-omics integration for aiding study design of large scale TCGA cancer datasets. [PDF]
Han E, Kwon H, Jung I.
europepmc +1 more source
A Map of the Lipid-Metabolite-Protein Network to Aid Multi-Omics Integration. [PDF]
Anyaegbunam UA +10 more
europepmc +1 more source
Multi-Omics Integration Reveals Electroacupuncture Ameliorates Cognitive Impairment in Alzheimer's Disease via Gut-Brain Axis. [PDF]
Zhang S +6 more
europepmc +1 more source
Decoding the cholesterol-apoptosis axis in HCC: a machine learning-based multi-omics integration and single-cell transcriptomic analysis. [PDF]
Li Y, Shi J, Zhao A, Huang J, Dai L.
europepmc +1 more source
Composition-on-composition regression analysis for multi-omics integration of metagenomic data. [PDF]
Rios N +5 more
europepmc +1 more source
A multi-omics integration framework using multi-label guided learning and multi-scale fusion. [PDF]
Li Y, Wang Y, Liang T, Li Y, Du W.
europepmc +1 more source

