Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Best hypotheses search on iso-energy-grid for initial orbit determination and track association
, 2013 Debris populating the geostationary orbit is mainly observed by ground-based optical telescopes. Short measurement arcs, known as tracklets, provide line-of-sight information along with the associated rates of change.
Weigel, Martin +3 more
core
Superposed epoch analysis of high-speed-stream effects at geosynchronous orbit: Hot plasma, cold plasma, and the solar wind [PDF]
, 2008 Superposed epoch analyses of magnetospheric plasma analyzer (MPA) data from Los Alamos National Laboratory (LANL) satellites are performed to reveal the density, temperature and flow velocity behavior of the hot ion plasma (0.1–45 keV), the hot electron ...
Borovsky, Joseph E., Denton, Michael H.
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
DLR’s Advanced Telerobotic Concepts and Experiments for On-Orbit Servicing
, 2007 Summary. Space robotics will become a key technology for the exploration of outer space and the operation and maintenance of space stations, satellites and other plat-forms, saving costs and relieving man from dangerous tasks.
Hirzinger, Gerd +5 more
core
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
29.20 S85-02840 Shuttle on orbit
, 1985 The STS-8 Shuttle on orbit, as depicted on the cover of a publication, or a presentation slide, given by Dr ...
core
Analogy to bi-elliptic transfers incorporating high- and low-thrust
, 2013 This note introduces an orbit transfer enabled through the use of high and low thrust propulsion technologies. To date, research in the area of high and low-thrust hybrid propulsion transfers has focused on the use of such systems for sequential orbit ...
Macdonald, Malcolm, Owens, Steven Robert
core +1 more source
Ascent trajectory optimisation for a single-stage-to-orbit vehicle with hybrid propulsion [PDF]
, 2012 This paper addresses the design of ascent trajectories for a hybrid-engine, high performance, unmanned, single-stage-to-orbit vehicle for payload deployment into low Earth orbit. A hybrid optimisation technique that couples a population-based, stochastic
Taylor, Ian +9 more
core +1 more source
Research of Design and Control System of Grab Mechanism of On-orbit Assembly Robot
Jixie chuandong, 2019 According to the requirement of the key technology research mission of on-orbit assembly space telescope and in order to implement the on-orbit assembly service effectively，the ground verification scheme of the on-orbit assembly robot and sub-mirror ...
Jiaqi Zhu +4 more
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