Results 71 to 80 of about 2,803,249 (308)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Viable 3C-SiC-on-Si MOSFET design disrupting current Material Technology Limitations [PDF]

, 2019
The cubic polytype (3C-) of Silicon Carbide (SiC) is an emerging semiconductor technology for power devices. The featured isotropic material properties along with the Wide Band Gap (WBG) characteristics make it an excellent choice for power Metal Oxide ...
Antoniou, M, Arvanitopoulos, A, Gyftakis, K N, Jennings, M R, Li, Fan, Lophitis, N, Perkins, S   +6 more
core   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

‘Caveat emptor’: the cautionary tale of endocarditis and the potential pitfalls of clinical coding data—an electronic health records study

BMC Medicine, 2019
Background Diagnostic codes from electronic health records are widely used to assess patterns of disease. Infective endocarditis is an uncommon but serious infection, with objective diagnostic criteria. Electronic health records have been used to explore
Nicola Fawcett, Bernadette Young, Leon Peto, T. Phuong Quan, Richard Gillott, Jianhua Wu, Chris Middlemass, Sheila Weston, Derrick W. Crook, Tim E. A. Peto, Berit Muller-Pebody, Alan P. Johnson, A. Sarah Walker, Jonathan A. T. Sandoe   +13 more
doaj   +1 more source

Antibiotic-resistant Escherichia Coli from Retail Poultry Meat with Different Antibiotic Use Claims [PDF]

, 2018
Background We sought to determine if the prevalence of antibiotic-resistant Escherichia coli differed across retail poultry products and among major production categories, including organic, “raised without antibiotics”, and conventional.
Davis, Gregg S., Grande, Heidi, Horwinski, Joseph, Hungate, Bruce A., Koch, Benjamin, Liu, Cindy M., Nordstrom, Lora, Papp, Katerina, Price, Lance B., Waits, Kara, Weaver, Brett   +10 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Novel 4H-SiC SGT MOSFET with Improved P+ Shielding Region and Integrated Schottky Barrier Diode

Micromachines
A silicon carbide (SiC) SGT MOSFET featuring a “一”-shaped P+ shielding region (PSR), named SPDT-MOS, is proposed in this article. The improved PSR is introduced as a replacement for the source trench to enhance the forward performance of the device.
Xiaobo Cao, Jing Liu, Yingnan An, Xing Ren, Zhonggang Yin   +4 more
doaj   +1 more source

Comparative Genomics of Environmental and Clinical Burkholderia cenocepacia Strains Closely Related to the Highly Transmissible Epidemic ET12 Lineage

Frontiers in Microbiology, 2018
The Burkholderia cenocepacia epidemic ET12 lineage belongs to the genomovar IIIA including the reference strain J2315, a highly transmissible epidemic B. cenocepacia lineage.
Josselin Bodilis, Josselin Bodilis, Elodie Denet, Elisabeth Brothier, Arnault Graindorge, Sabine Favre-Bonté, Sylvie Nazaret   +6 more
doaj   +1 more source

On the Trade-Off Between Quality Factor and Tuning Ratio in Tunable High-Frequency Capacitors [PDF]

, 2009
A benchmark of tunable and switchable devices at microwave frequencies is presented on the basis of physical limitations to show their potential for reconfigurable cellular applications.
Hueting, R.J.E., Reimann, K., Schmitz, J., Tiggelman, M.P.J., Van Rijs, F.   +4 more
core   +3 more sources