Results 81 to 90 of about 51,151,627 (314)
The 4th ASM Conference on Antimicrobial Resistance in Zoonotic Bacteria and Foodborne Pathogens will continue and expand the excellent existing scientific agenda to include emphases on novel approaches to molecular typing, whole genome sequencing and its
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Resisting Bacterial Drug Resistance [PDF]
In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
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This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
A Public health action plan to combat antimicrobial resistance : Domestic issues; Part 1 [PDF]
The Interagency Task Force on Antimicrobial Resistance is co-chaired by the Centers for Disease Control and Prevention, Food and Drug Administration, and the National Institutes of Health. It also includes the Agency for Healthcare Research and Quality ..
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Resistance and cross‐resistance to abacavir [PDF]
Background Abacavir (ABC) is a potent nucleoside reverse transcriptase inhibitor (NRTI) used in multi‐drug antiretroviral regimens and in combination with other NRTIs, protease and/or non‐nucleoside reverse transcriptase inhibitors (NNRTIs) in both treatment naive and treatment experienced patients.Patterns of resistance Resistance to ABC has been ...
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Background Using case-vignettes, we assessed the perception of European infection control (IC) specialists regarding the individual and collective risk associated with antimicrobial resistance (AMR) among inpatients.
Gabriel Birgand +6 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Effect of aluminium sheet surface conditions on feasibility and quality of resistance spot welding [PDF]
A study investigating the effect of sheet surface condition on resistance spot welding (RSW) of aluminium has been carried out. This concentrates on two automotive aluminium alloys; AA5754 and AA6111, used for structural and closure applications ...
Shergold, Mike +3 more
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