Results 101 to 110 of about 77,923,058 (250)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Recovery voltage measurement on oil-paper insulation with simple geometry and controlled environment

open access: yes, 2004
Using the recovery voltage of oil-paper insulation to diagnose its state of maintenance is very popular among electrical engineers. Many advantages of using recovery voltage includes non-intrusive, easy to operate, more resistant to noise compare to ...
Kuang, Y C, Jarman, P, Chen, G
core   +1 more source

Harmonic voltage phasor reconstruction and harmonic state estimation based on the measurement data of a capacitive voltage transformer

open access: yesIET Electric Power Applications
Harmonic state estimation, which highly depends on accurate synchronised phasors, is a crucial basis for the location, traceability, and governance of harmonics in power systems.
Xiaoxian Zhu   +6 more
doaj   +1 more source

Impact of the Scaling of LGS and LG on the On-State Breakdown Voltage of InAlN/GaN HFETs With Localized Fin Under the Gate Electrode

open access: yesIEEE Journal of the Electron Devices Society
In this manuscript, we have investigated the impact of the scaling of the gate-source length (LGS) and gate length (LG) on the on-state breakdown voltage (BVon) of metallic-face InAlN/AlN/GaN heterostructure field effect transistors (HFETs) having fin ...
Yatexu Patel, Pouya Valizadeh
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Low-voltage variable capacitance diode

open access: yes, 2004
Low-voltage variable capacitance diode Product ...
Voltage Controlled Oscillators (vco
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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