Myopia Outcome Study of Atropine in Children (MOSAIC): an investigator-led, double-masked, placebo-controlled, randomised clinical trial protocol [version 1; peer review: 2 approved, 1 approved with reservations] [PDF]
HRB Open Research, 2019 Background: The Myopia Outcome Study of Atropine in Children (MOSAIC) aims to explore the efficacy, safety, acceptability and mechanisms of action of 0.01% unpreserved atropine for myopia control in a European population.
Saoirse McCrann +8 more
doaj +3 more sources
Myopia Outcome Study of Atropine in Children (MOSAIC): an investigator-led, double-masked, placebo-controlled, randomised clinical trial protocol [version 2; peer review: 2 approved, 1 approved with reservations] [PDF]
HRB Open Research, 2019 Background: The Myopia Outcome Study of Atropine in Children (MOSAIC) aims to explore the efficacy, safety, acceptability and mechanisms of action of 0.01% unpreserved atropine for myopia control in a European population.
Saoirse McCrann +8 more
doaj +6 more sources
Recurrence of Acute Duodenal Ulcer [PDF]
Canadian Journal of Gastroenterology, 1994 Nizatidine, 300 mg once nightly, was compared with cimetidine, 800 mg once nightly, for treatment of 212 adult out-patients with acute duodenal ulcers in an eight-week randomized, double-blind, multicentre trial.
RJ Bailey +8 more
doaj +2 more sources
Efficacy of Topical 5% 5-Fluorouracil and 0.05% Tretinoin and Electrosurgery in the Treatment of Plane Warts: A Randomized Controlled Comparative Trial [PDF]
Nepal Journal of Dermatology, Venereology & Leprology, 2021 Human papilloma virus (HPV) is capable of causing varieties of dermatological conditions differing in morphology, histopathology and site of occurrence.
Rashmi Singh, Shyam Sundar Pandey
doaj +5 more sources
Clinical TherapeuticsIndividuals with narcolepsy are more likely to be obese than the general population. Changes in weight-related measures with extended-release, once-nightly sodium oxybate (ON-SXB) and characteristics of participants with ≥5% weight loss were assessed in a Randomized study Evaluating the efficacy and SafeTy of a ONce nightly formulation of sodium ...
Richard K Bogan +2 more
exaly +3 more sources
0411 Once-Nightly Sodium Oxybate Dose Titration and Tolerability: Interim Data From RESTORE
Sleep, 2022 Abstract Introduction Extended-release, once-nightly sodium oxybate (ON-SXB; FT218) is under FDA review for the treatment of adults with narcolepsy. RESTORE, an ongoing, open-label extension/switch study (NCT04451668), evaluates long-term ON-SXB safety and tolerability.
Asim Roy +6 more
+5 more sources
Neurology and Therapy, 2023 Narcolepsy is associated with disrupted nighttime sleep (DNS). Sodium oxybate (SXB; Xyrem®), administered twice nightly, is indicated for the treatment of cataplexy and excessive daytime sleepiness in patients 7 years or older with narcolepsy.
Russell Rosenberg +5 more
doaj +1 more source
‘I love you’: the first phrase detected from dreams [PDF]
Sleep Science, 2022 Objective: Many people have dreams nightly and some maintain consciousness during dreams. Such dreams are referred to as lucid dreams (LD). During dreams, our speech correlates with facial muscle activity, which is hard to decode, but LD could solve this
Michael Raduga
doaj +1 more source
Foraging movements are density-independent among straw-coloured fruit bats [PDF]
Royal Society Open Science, 2020 Intraspecific competition in large aggregations of animals should generate density-dependent effects on foraging patterns. To test how large differences in colony size affect foraging movements, we tracked seasonal movements of the African straw-coloured
María C. Calderón-Capote +5 more
doaj +1 more source
Badger territoriality maintained despite disturbance of major road construction.
PLoS ONE, 2021 Road ecology has traditionally focused on the impact of in-situ and functional roads on wildlife. However, road construction also poses a major, yet understudied, threat and the implications for key aspects of animal behaviour are unknown. Badgers (Meles
Aoibheann Gaughran +7 more
doaj +1 more source