Results 21 to 30 of about 9,404 (185)

Evidence of Accidental Dosing Errors with Immediate-Release Sodium Oxybate: Data from the US Food and Drug Administration Adverse Event Reporting System

Drugs - Real World Outcomes, 2023
Introduction Sodium oxybate has been approved by the US Food and Drug Administration (FDA) to treat narcolepsy for 20 years; however, the only available products have been immediate-release (IR) formulations given twice nightly—once at bedtime and a ...
Jennifer Gudeman, Danielle Burroughs
doaj   +1 more source

The Polarisation Signatures of Microlensing [PDF]

, 1998
It has already been shown that microlensing can give rise to a non-zero variable polarisation signal. Here we use realistic simulations to demonstrate the additional information that can be gained from polarimetric observations of lensing events.Comment:
A.M. Newsam, Coleman, Gould, I.J. Coleman, J.F.L. Simmons, M.A. Hendry, Simmons, Udalski, Valls-Gabaud, Witt   +9 more
core   +3 more sources

The Effects of 0.01% Atropine on Adult Myopes’ Contrast Sensitivity

Frontiers in Neuroscience, 2021
PurposeAtropine at a low concentration is considered a safe and effective treatment to mitigate myopia progression. However, the potential unwanted side effects of administering atropine at a low dose on visual functions other than best corrected visual ...
Ziyun Cheng, Jianhui Mei, Suqi Cao, Ran Zhang, Jiawei Zhou, Yuwen Wang   +5 more
doaj   +1 more source

Phase II Proof-of-Concept Trial of the Orexin Receptor Antagonist Filorexant (MK-6096) in Patients with Major Depressive Disorder. [PDF]

, 2017
BackgroundWe evaluated the orexin receptor antagonist filorexant (MK-6096) for treatment augmentation in patients with major depressive disorder.MethodsWe conducted a 6-week, double-blind, placebo-controlled, parallel-group, Phase II, proof-of-concept ...
Ceesay, Paulette, Connor, Kathryn M, Herring, W Joseph, Hutzelmann, Jill, Krystal, Andrew D, Lines, Christopher, Michelson, David, Snavely, Duane, Thase, Michael, Trivedi, Madhukar H   +9 more
core   +1 more source

Protocol for a parallel assignment prospective, randomised, double-blinded, placebo-controlled trial to evaluate the efficacy of 0.01% atropine for near work-induced transient myopia and myopic progression in China

BMJ Open, 2023
Introduction Assessment of near work-induced transient myopia (NITM) is important for permanent myopia development and progression. Atropine eye drop has been reported to be beneficial in reducing initial NITM and slowing down myopic progression.
Sile Yu, Wei He, Lan Hu, Ling Xu, Jiayan Chen, Guanghao Qin, Yifan Qi, Emmanuel Eric Pazo, Xingru He   +8 more
doaj   +1 more source

Heterozygous frameshift mutation in keratin 5 in a family with Galli-Galli disease [PDF]

, 2014
BACKGROUND: Reticulate pigmentary disorders include the rare autosomal dominant Galli–Galli disease (GGD) and Dowling–Degos disease (DDD). Clinical diagnosis between some of the subtypes can be difficult due to a degree of overlap between clinical ...
Kokkonen, E. W. J., McLean, W. H. I., Reisenauer, A. K., Smith, F. J. D., Wilson, N. J., Wordingham, S. V., York, J.   +6 more
core   +2 more sources

Preferences for Attributes of Sodium Oxybate Treatment: A Discrete Choice Experiment in Patients with Narcolepsy

Patient Preference and Adherence, 2022
Jordan Dubow,1 Alon Y Avidan,2 Bruce Corser,3 Amod Athavale,4 David Seiden,1 Clete Kushida5 1Avadel Pharmaceuticals, Chesterfield, MO, USA; 2Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 3Sleep Management ...
Dubow J, Avidan AY, Corser B, Athavale A, Seiden D, Kushida C   +5 more
doaj  

Effects of atropine 0.01% on refractive errors in children with myopia

Heliyon, 2023
Background: Little is known about changes in astigmatism during atropine treatment. We aimed to explore the effects of atropine 0.01% eye drops on both spherical and cylindrical refractive errors in myopic children. Methods: Children aged 6–14 years with
Xingxue Zhu, Yuliang Wang, Yujia Liu, Chaoying Ye, Xingtao Zhou, Xiaomei Qu   +5 more
doaj   +1 more source

Reduced anterior cingulate grey matter volume in painful hand osteoarthritis [PDF]

, 2018
Objective Increasing evidence supports the role of central sensitisation in osteoarthritis (OA) pain. In this study, we used neuroimaging to compare pain-processing regions of the brain in participants with and without hand OA.
Barrick, T, Howe, FA, Russell, M, Sofat, N   +3 more
core   +1 more source

Safety and efficacy of 0.02% and 0.01% atropine on controlling myopia progression: a 2-year clinical trial

Scientific Reports, 2021
Four hundred myopic children randomly received atropine 0.02% (n = 138) or 0.01% (n = 142) in both eyes once-nightly or only wore single-vision spectacles (control group) (n = 120) for 2 years.
Can Cui, Xiujuan Li, Yong Lyu, Li Wei, Bingxin Zhao, Shiao Yu, Junbo Rong, Yanhui Bai, Aicun Fu   +8 more
doaj   +1 more source