Results 21 to 30 of about 17,110 (255)

Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells. [PDF]

PLoS ONE, 2012
Ivermectin is currently approved for treatment of both clinical and veterinary infections by nematodes, including Onchocerca cervicalis in horses and Onchocerca volvulus in humans.
Matthew A Pettengill, Verissa W Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, David M Ojcius   +4 more
doaj   +1 more source

Co-infection with Onchocerca volvulus and Loa loa microfilariae in central Cameroon: are these two species interacting? [PDF]

, 2006
Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L.
Basáñez, M-G, Boussinesq, M, Clarke, P, Filipe, JAN, Gardon, J, Kamgno, J, Pion, SDS   +6 more
core   +1 more source

The therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness [PDF]

, 2014
Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival.
Achim Hoerauf, Agwuh, Basáñez, Basáñez, Bosshardt, Cattamanchi, Chib, Churcher, de Andrade, Debrah, Duke, Duke, Gardon, Gelman, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Mand, Mark J. Taylor, Martin Walker, María-Gloria Basáñez, Norton, Osei-Atweneboana, Plaisier, Plaisier, Roberts, Sabine Specht, Specht, Tamarozzi, Taylor, Taylor, Taylor, Taylor, Taylor, Thomas S. Churcher, van Rie, Wanji, Wearing, World Health Organization, Xia   +43 more
core   +2 more sources

Zoonotic Implications of Onchocerca Species on Human Health

Pathogens, 2020
The genus Onchocerca includes several species associated with ungulates as hosts, although some have been identified in canids, felids, and humans. Onchocerca species have a wide geographical distribution, and the disease they produce, onchocerciasis, is
Maria Cambra-Pellejà, Javier Gandasegui, Rafael Balaña-Fouce, José Muñoz, María Martínez-Valladares   +4 more
doaj   +1 more source

Zoonotic onchocerciasis in Hiroshima, Japan, and molecular analysis of a paraffin section of the agent for a reliable identification

Parasite, 2011
Japan is a country of high specific diversity of Onchocerca with eight species, the adults of two not yet known. Onchocerca dewittei japonica, a common filarial parasite of wild boar, had been proved to be the agent of five zoonotic onchocerciasis in ...
Fukuda M., Otsuka Y., Uni S., Boda T., Daisaku H., Hasegawa H., Takaoka H., Bain O.   +7 more
doaj   +1 more source

A cryptic species of Onchocerca (Nematoda: Onchocercidae) in blackflies (Simulium spp.) from southern California, USA

Parasites & Vectors, 2018
Background Entomological surveillance for pathogens based on molecular screening of putative arthropod vectors such as blackflies (Diptera: Simuliidae) is becoming increasingly important.
Guilherme G Verocai, Kimberly J Nelson, R Trey Callahan, Joseph Wakoli Wekesa, Hassan K Hassan, Eric P Hoberg   +5 more
doaj   +1 more source

Recombinant expression systems: the obstacle to helminth vaccines? [PDF]

, 2007
A
Claerebout, Edwin, De Maere, Veerle, Geldhof, Peter, Vercruysse, Jozef   +3 more
core   +2 more sources

Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis.

PLoS Pathogens, 2021
Onchocerciasis (river blindness), caused by the filarial worm Onchocerca volvulus, is a neglected tropical disease mostly affecting sub-Saharan Africa and is responsible for >1.3 million years lived with disability. Current control relies almost entirely
Germanus S Bah, Sebastian Schneckener, Steffen R Hahnel, Nicolas H Bayang, Helena Fieseler, Gabriele M Schmuck, Ralph Krebber, Anouk Sarr, Carsten Terjung, Henrietta F Ngangyung, David D Ekale, Youssouf M Mfopit, Lucien Rufener, John Graham-Brown, Vincent N Tanya, Martin Glenschek-Sieberth, Daniel Kulke, Benjamin L Makepeace   +17 more
doaj   +1 more source

Epilepsy in Onchocerca volvulus Sero-Positive Patients From Northern Uganda—Clinical, EEG and Brain Imaging Features

Frontiers in Neurology, 2021
Globally, epilepsy is the most common chronic neurological disorder. The incidence in sub-Saharan Africa is 2-3 times higher than that in high income countries.
Rodney Ogwang, Rodney Ogwang, Rodney Ogwang, Albert Ningwa, Albert Ningwa, Pamela Akun, Pamela Akun, Paul Bangirana, Ronald Anguzu, Ronald Anguzu, Ronald Anguzu, Rajarshi Mazumder, Noriko Salamon, Oliver Johannes Henning, Charles R. Newton, Charles R. Newton, Catherine Abbo, Amos Deogratius Mwaka, Kevin Marsh, Richard Idro, Richard Idro, Richard Idro   +21 more
doaj   +1 more source

The Population Biology and Transmission Dynamics of Loa loa [PDF]

, 2017
Endemic to Central Africa, loiasis – or African eye worm (caused by the filarial nematode Loa loa) – affects more than 10 million people. Despite causing ocular and systemic symptoms, it has typically been considered a benign condition, only of public ...
Basáñez, M-G, Boussinesq, M, Chesnais, C B, Pion, S D S, Walker, M, Whittaker, C   +5 more
core   +1 more source