Results 31 to 40 of about 20,920 (295)

Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells. [PDF]

PLoS ONE, 2012
Ivermectin is currently approved for treatment of both clinical and veterinary infections by nematodes, including Onchocerca cervicalis in horses and Onchocerca volvulus in humans.
Matthew A Pettengill, Verissa W Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, David M Ojcius   +4 more
doaj   +1 more source

Small RNAs and extracellular vesicles in filarial nematodes: from nematode development to diagnostics [PDF]

, 2016
Parasitic nematodes have evolved sophisticated mechanisms to communicate with their hosts in order to survive and successfully establish an infection. The transfer of RNA within extracellular vesicles (EVs) has recently been described as a mechanism that
Babayan, S.A., Buck, A.H., Quintana, J.F.   +2 more
core   +2 more sources

Co-infection with Onchocerca volvulus and Loa loa microfilariae in central Cameroon: are these two species interacting? [PDF]

, 2006
Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L.
Basáñez, M-G, Boussinesq, M, Clarke, P, Filipe, JAN, Gardon, J, Kamgno, J, Pion, SDS   +6 more
core   +1 more source

Comparison of Diagnostic Tests for Onchocerca volvulus in the Democratic Republic of Congo

Pathogens, 2020
Onchocerciasis is diagnosed by detecting microfilariae in skin snips or by detecting OV16 IgG4 antibodies in blood by either enzyme linked immunosorbent assay (ELISA) or a rapid diagnostic test (RDT).
A. Hotterbeekx, Jolien Perneel, M. Mandro, Germain M Abhafule, J. S. Siewe Fodjo, Alfred Dusabimana, S. Abrams, S. Kumar-Singh, R. Colebunders   +8 more
semanticscholar   +1 more source

Zoonotic onchocerciasis in Hiroshima, Japan, and molecular analysis of a paraffin section of the agent for a reliable identification

Parasite, 2011
Japan is a country of high specific diversity of Onchocerca with eight species, the adults of two not yet known. Onchocerca dewittei japonica, a common filarial parasite of wild boar, had been proved to be the agent of five zoonotic onchocerciasis in ...
Fukuda M., Otsuka Y., Uni S., Boda T., Daisaku H., Hasegawa H., Takaoka H., Bain O.   +7 more
doaj   +1 more source

Crystal structure of N-terminally hexahistidine-tagged Onchocerca volvulus macrophage migration inhibitory factor-1. [PDF]

Acta Crystallogr F Struct Biol Commun
N‐terminally hexahistidine‐tagged O. volvulus macrophage migration inhibitory factor‐1 has a unique jellyfish‐like structure with the prototypical macrophage migration inhibitory factor trimer as the `head' and a C‐terminal extension as the `tail'.Onchocerca volvulus causes blindness, onchocerciasis, skin infections and devastating neurological ...
Kimble AD, Dawson OCO, Liu L, Subramanian S, Cooper A, Battaile K, Craig J, Harmon E, Myler P, Lovell S, Asojo OA.   +10 more
europepmc   +2 more sources

Recombinant expression systems: the obstacle to helminth vaccines? [PDF]

, 2007
A
Claerebout, Edwin, De Maere, Veerle, Geldhof, Peter, Vercruysse, Jozef   +3 more
core   +2 more sources

Detection of <i>Dirofilaria repens</i> and <i>Mansonella llewellyni</i> in the United States by <i>Wolbachia</i> Surveillance. [PDF]

Transbound Emerg Dis
In mammals, detection of Wolbachia bacteria can be used to diagnose filarial infection, while antibiotic treatment to eliminate Wolbachia can assist in eliminating filarial infections. Because Wolbachia are necessary for survival of several filarioids and closely related to Anaplasma and Ehrlichia, we analyzed Wolbachia DNA amplification by Anaplasma ...
Moore CO, Robveille C, Qurollo B, Breitschwerdt EB.   +3 more
europepmc   +2 more sources

The Population Biology and Transmission Dynamics of Loa loa [PDF]

, 2017
Endemic to Central Africa, loiasis – or African eye worm (caused by the filarial nematode Loa loa) – affects more than 10 million people. Despite causing ocular and systemic symptoms, it has typically been considered a benign condition, only of public ...
Basáñez, M-G, Boussinesq, M, Chesnais, C B, Pion, S D S, Walker, M, Whittaker, C   +5 more
core   +1 more source

Immunoselective progression of a multi-epitope-based subunit vaccine candidate to convey protection against the parasite Onchocerca lupi

Informatics in Medicine Unlocked, 2023
Globalization has resulted in an increasing worldwide movement of humans and animals as well as changes in the external environment, temperature, and social interactions, resulting in the accelerated emergence of new diseases in humans and dogs, such as ...
Mohammad Nahian Rahman, Shakil Ahmed, Mahamudul Hasan, Md. Sabbir Ahmed Shuvo, Md. Anwarul Islam, Rakibul Hasan, Shiplu Roy, Hemayet Hossain, Md. Mukthar Mia   +8 more
doaj   +1 more source