Results 81 to 90 of about 13,454 (262)

Onchocerca volvulus is not detected in the cerebrospinal fluid of persons with onchocerciasis-associated epilepsy

International Journal of Infectious Diseases, 2020
Objectives: Epidemiological evidence links onchocerciasis with the development of epilepsy. The aim of this study was to detect Onchocerca volvulus microfilariae or its bacterial endosymbiont, Wolbachia, in the cerebrospinal fluid (CSF) of persons with ...
An Hotterbeekx, Stephen Raimon, Gasim Abd-Elfarag, Jane Y. Carter, Wilson Sebit, Abozer Suliman, Joseph Nelson Siewe Fodjo, Peter De Witte, Makoy Yibi Logora, Robert Colebunders, Samir Kumar-Singh   +10 more
doaj   +1 more source

A histochemical study of the Nras/let-60 activity in filarial nematodes [PDF]

, 2015
BACKGROUND: Control and elimination of filarial pathogens is a central focus of major global health efforts directed at parasitic diseases of developing countries.
Charles Mackenzie, James Geary, Maeghan O’Neill, Nicole Madrill, Raquel Lovato, Ron Guderian, Sabine Specht, Samuel Wanji, Timothy Geary   +8 more
core   +1 more source

Community‐based epilepsy care in an onchocerciasis‐endemic area: A 3‐year cohort study in Mahenge, Tanzania

Epilepsia, Volume 66, Issue 3, Page 739-752, March 2025.
Abstract Objective In onchocerciasis‐endemic areas, limited access to antiseizure medications (ASMs) contributes to a high epilepsy burden. This study evaluated the impact of a community‐based epilepsy care program in Mahenge, Tanzania, an onchocerciasis‐endemic area with high epilepsy prevalence.
Dan Bhwana, Luís‐Jorge Amaral, Olivia Kamoen, Athanas Mhina, Vivian Mushi, William Makunde, William Matuja, Meshack Mpogole, Bruno P. Mmbando, Robert Colebunders   +9 more
wiley   +1 more source

Ivermectin as a promising therapeutic option for onchocerciasis‐associated epilepsy

Epilepsia Open, Volume 10, Issue 1, Page 361-367, February 2025.
Abstract Onchocerciasis, commonly known as river blindness, is a neglected tropical disease caused by the parasite Onchocerca volvulus. It can lead to blindness and visual impairment. Studies have also demonstrated a link between onchocerciasis and epilepsy, with there being a correlation between onchocerciasis endemicity and epilepsy prevalence ...
Mohammad Amin Manavi, Razieh Mohammad Jafari, Hamed Shafaroodi, Mohammad Sharifzadeh, Ahmad Reza Dehpour   +4 more
wiley   +1 more source

Nodules sous-cutanés et lésions cutanées engendrés par diverses onchocerques chez des bovins africains

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1994
Des nodules sous-cutanés et de la peau ombilicale sont prélevés sur 6 Bos indicus onchocerquiens au Cameroun, pour l'étude anatomopathologiq ue. Les nodules à Onchocerca ochengi et Onchocerca dukei ont la même structure que celle des nodules à Onchocerca
P.N. Vuong, S. Wanji, J. Prod'Hon, O. Bain   +3 more
doaj   +1 more source

Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.

PLoS Pathogens, 2021
Current mass drug administration (MDA) programs for the treatment of human river blindness (onchocerciasis) caused by the filarial worm Onchocerca volvulus rely on ivermectin, an anthelmintic originally developed for animal health.
Jürgen Krücken, Lindy Holden-Dye, Jennifer Keiser, Roger K Prichard, Simon Townson, Benjamin L Makepeace, Marc P Hübner, Steffen R Hahnel, Ivan Scandale, Achim Harder, Daniel Kulke   +10 more
doaj   +1 more source

MRI Findings in People with Epilepsy and Nodding Syndrome in an Area Endemic for Onchocerciasis: An Observational Study. [PDF]

, 2013
Onchocerciasis has been implicated in the pathogenesis of epilepsy. The debate on a potential causal relationship between Onchocerca volvulus and epilepsy has taken a new direction in the light of the most recent epidemic of nodding syndrome. To document
Dharsee, J, Friedrich, K, Gotwald, T, Jilek-Aall, L, Kidunda, A, König, R, Matuja, W, Meindl, M, Müller, T H, Nassri, A, Schmutzhard, E, Velicheti, S, Winkler, A S   +12 more
core   +2 more sources

Exploring Glaucoma: From Pathogenesis to Emerging Diagnostic and Management Strategies

Journal of Ophthalmology, Volume 2025, Issue 1, 2025.
Glaucoma is a leading cause of irreversible blindness globally, affecting millions of individuals. It encompasses a group of progressive optic neuropathies characterized by retinal ganglion cell loss and visual field deterioration, often associated with elevated intraocular pressure.
Rajesh Kumar Goit, Nilufer Yesilirmak
wiley   +1 more source

Monoclonal Antibodies as Investigative Tools in Onchocerciasis [PDF]

, 2017
The development of monoclonal antibodies against parasites can facilitate analysis of host-parasite interactions and can lead to the identification and characterization of antigens that induce protective responses in the immunized host.
Weiss, Niklaus
core  

The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes [PDF]

, 2010
The cuticle of parasitic nematodes performs many critical functions and is essential for proper development and for protection from the host immune response.
Antony P. Page, Bernard, Blaxter, Chu, Cook, Fessler, Ford, Frand, Ghedin, Gillian McCormack, Gillian Stepek, Hawdon, Johnstone, Johnstone, Kingston, Kingston, Kramerova, Kramerova, Kress, Mieszczanek, Milstone, Nagano, Novelli, Novelli, Paesen, Page, Page, Poole, Priess, Redmond, Rhoads, Sasaki, Scott, Shamansky, Skuce, Stanssens, Studier, Thacker, Thacker, Thacker, Thacker, Thein, Wells, Winter   +43 more
core   +1 more source