Results 61 to 70 of about 14,649 (169)

Onchocerca volvulus is not detected in the cerebrospinal fluid of persons with onchocerciasis-associated epilepsy

International Journal of Infectious Diseases, 2020
Objectives: Epidemiological evidence links onchocerciasis with the development of epilepsy. The aim of this study was to detect Onchocerca volvulus microfilariae or its bacterial endosymbiont, Wolbachia, in the cerebrospinal fluid (CSF) of persons with ...
An Hotterbeekx, Stephen Raimon, Gasim Abd-Elfarag, Jane Y. Carter, Wilson Sebit, Abozer Suliman, Joseph Nelson Siewe Fodjo, Peter De Witte, Makoy Yibi Logora, Robert Colebunders, Samir Kumar-Singh   +10 more
doaj   +1 more source

Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.

PLoS Pathogens, 2021
Current mass drug administration (MDA) programs for the treatment of human river blindness (onchocerciasis) caused by the filarial worm Onchocerca volvulus rely on ivermectin, an anthelmintic originally developed for animal health.
Jürgen Krücken, Lindy Holden-Dye, Jennifer Keiser, Roger K Prichard, Simon Townson, Benjamin L Makepeace, Marc P Hübner, Steffen R Hahnel, Ivan Scandale, Achim Harder, Daniel Kulke   +10 more
doaj   +1 more source

PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection

European Journal of Immunology, Volume 55, Issue 8, August 2025.
During filarial nematode infection with Litomosoides sigmodontis, PD‐L2 down‐regulates Th2 cell expression of GATA‐3 and Th2 cytokines and enables parasite survival. Concurrently, B cells suppress protective immunity through a mechanism that does not involve PD‐L2.
Johanna A. Knipper, Sharon M. Campbell, Judith E. Allen, Matthew D. Taylor   +3 more
wiley   +1 more source

Cloning and characterization of an Onchocerca volvulus specific DNA sequence

, 2019
A cloned sequence, pOvs134, was isolated from a genomic library prepared from Onchocerca volvulus of savanna origin in the plasmid pUC9. pOvs134 hybridizes to all the geographic isolates of O.
Meredith, Stefanie E.O., Karam, Marc, Piessens, Willy F., Unnasch, Thomas R., Wirth, Dyann F.   +4 more
core   +1 more source

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza, Michael Olubusayo Binuyo, Callixte Cyuzuzo, Acsa Igizeneza, Jean Paul Sinumvayo, Oluwaremilekun Grace Ajakaye, Egie Elisha Enabulele, Zororo Chinwadzimba, Ezera Agwu, Nicholas Midzi   +9 more
wiley   +1 more source

Nodules sous-cutanés et lésions cutanées engendrés par diverses onchocerques chez des bovins africains

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1994
Des nodules sous-cutanés et de la peau ombilicale sont prélevés sur 6 Bos indicus onchocerquiens au Cameroun, pour l'étude anatomopathologiq ue. Les nodules à Onchocerca ochengi et Onchocerca dukei ont la même structure que celle des nodules à Onchocerca
P.N. Vuong, S. Wanji, J. Prod'Hon, O. Bain   +3 more
doaj   +1 more source

Lords of the flies: dipteran migrants are diverse, abundant and ecologically important

Biological Reviews, Volume 100, Issue 4, Page 1635-1659, August 2025.
ABSTRACT Insect migrants are hugely abundant, with recent studies identifying the megadiverse order Diptera as the major component of many migratory assemblages. Despite this, their migratory behaviour has been widely overlooked in favour of more ‘charismatic’ migrant insects such as butterflies, dragonflies, and moths.
Will L. Hawkes, Myles H.M. Menz, Karl R. Wotton   +2 more
wiley   +1 more source

The Interconnected World of Dermatology and Ophthalmology

JEADV Clinical Practice, Volume 4, Issue 2, Page 389-399, June 2025.
Medical science, is an integrated field that shares intricate relationship between various organ systems. Similarly, dermatology is inter‐related with various other specialties including ophthalmology. This article depicts the correlation of ophthalmology and dermatology iterating on the genetic diseases, autoimmune diseases, systemic disorders ...
Gyanesh Rathore, Surajit Gorai, Gitikash Purkayastha, Kinnor Das, Prajwal Pudasaini   +4 more
wiley   +1 more source

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract Recent years have seen major advances in tau‐associated brain disorders through interdisciplinary research spanning molecular biology, neuroimaging, clinical trials, and therapeutic development. The Tau2024 Global Conference, hosted by the Alzheimer's Association, CurePSP, and Rainwater Charitable Foundation, showcased these efforts by ...
Bess Frost, James B. Rowe, Rufus O. Akinyemi, Jose F. Abisambra, Nicholas J. Ashton, Matthias Brendel, Luc Buée, David Butler, Maria C. Carrillo, Peter Chung, Claire D. Clelland, Sarah L. DeVos, Kristophe Diaz, Rebecca M. Edelmayer, Fanny M. Elahi, Ratnavalli Ellajosyula, Colin Ewen, Igor Camargo Fontana, Marie‐Christine Galas, Oskar Hansson, Günter Höglinger, Kanta Horie, Agustín Ibanez, Linde Jacobs, Mahmoud B. Maina, Maura Malpetti, Eric McDade, Will McEwan, Laia Montoliu‐Gaya, Catherine J. Mummery, Miranda E. Orr, Jonathan D. Rohrer, Amy Rommel, Carlos Sastre, Tara L. Spires‐Jones, Boon Lead Tee, Tim J. Viney, Jamie M. Walker, Susanne Wegmann, Kristin Wildsmith, Ravi Yadav, Simin Mahinrad, Claire Sexton   +42 more
wiley   +1 more source

Zoonotic onchocerciasis caused by a parasite from wild boar in Oita, Japan

Parasite, 2004
Histological examination of a nodule removed from the back of the hand of a 58-year-old woman from Oita, Kyushu, Japan showed an Onchocerca female sectioned through the posterior region of the worm (ovaries identifiable) and young (thin cuticle).
Takaoka H., Bain O., Uni S., Korenaga M., Kozek W.J., Shirasaka C., Aoki C., Otsuka Y., Fukuda M., Eshita Y., Daa T.   +10 more
doaj   +1 more source