Results 41 to 50 of about 6,880 (180)

Of mice, cattle, and humans: the immunology and treatment of river blindness.

PLoS Neglected Tropical Diseases, 2008
River blindness is a seriously debilitating disease caused by the filarial parasite Onchocerca volvulus, which infects millions in Africa as well as in South and Central America. Research has been hampered by a lack of good animal models, as the parasite
Judith E Allen, Ohene Adjei, Odile Bain, Achim Hoerauf, Wolfgang H Hoffmann, Benjamin L Makepeace, Hartwig Schulz-Key, Vincent N Tanya, Alexander J Trees, Samuel Wanji, David W Taylor   +10 more
doaj   +1 more source

The Mbam drainage system and onchocerciasis transmission post ivermectin mass drug administration (MDA) campaign, Cameroon.

PLoS Neglected Tropical Diseases, 2021
BackgroundThe impact of large scale Mass Drug Adminstration (MDA) of ivermectin on active onchocerciasis transmission by Simulium damnosum, which transmits the parasite O. volvulus is of great importance for onchocerciasis control programmes.
Raphael Awah Abong, Glory Ngongeh Amambo, Ali Ahamat Hamid, Belinda Agbor Enow, Amuam Andrew Beng, Franck Noel Nietcho, Theobald Mue Nji, Abdel Jelil Njouendou, Manuel Ritter, Mathias Eyong Esum, Kebede Deribe, Jerome Fru Cho, Fanny Fri Fombad, Peter Ivo Enyong, Catherine Poole, Kenneth Pfarr, Achim Hoerauf, Clotilde Carlow, Samuel Wanji   +18 more
doaj   +1 more source

Master of Puppets: How Microbiota Drive the Nematoda Ecology and Evolution?

Ecology and Evolution, Volume 15, Issue 8, August 2025.
The nematode microbiota can influence life‐history traits, thereby shaping the species' ecology and evolutionary trajectories. ABSTRACT In recent decades, the microbiota has emerged as a key driver of biological functions in metazoans, and nematodes are no exception.
Víctor José Trejo‐Meléndez, Jorge Contreras‐Garduño   +1 more
wiley   +1 more source

Mansonella perstans, Onchocerca volvulus and Strongyloides stercoralis infections in rural populations in central and southern Togo

Parasite Epidemiology and Control, 2018
Background: Mansonella perstans, Onchocerca volvulus and Strongyloides stercoralis are widespread helminth parasites in the tropics. Their distribution remains difficult to determine as it may change during national disease control programs and with ...
Francois Korbmacher, Kossi Komlan, Richard G. Gantin, Wiyao P. Poutouli, Koffi Padjoudoum, Potchoziou Karabou, Peter T. Soboslay, Carsten Köhler   +7 more
doaj   +1 more source

PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection

European Journal of Immunology, Volume 55, Issue 8, August 2025.
During filarial nematode infection with Litomosoides sigmodontis, PD‐L2 down‐regulates Th2 cell expression of GATA‐3 and Th2 cytokines and enables parasite survival. Concurrently, B cells suppress protective immunity through a mechanism that does not involve PD‐L2.
Johanna A. Knipper, Sharon M. Campbell, Judith E. Allen, Matthew D. Taylor   +3 more
wiley   +1 more source

Research for new drugs for elimination of onchocerciasis in Africa

International Journal for Parasitology: Drugs and Drug Resistance, 2016
Onchocerciasis is a parasitic, vector borne disease caused by the filarial nematode Onchocerca volvulus. More than 99% of the population at risk of infection live in Africa. Onchocerciasis control was initiated in West Africa in 1974 with vector control,
Annette C. Kuesel
doaj   +1 more source

Nodding syndrome research revisited

International Journal of Infectious Diseases, 2021
Nodding syndrome is one of several forms of onchocerciasis-associated epilepsy (OAE) seen among children in areas formerly hyperendemic for the transmission of Onchocerca volvulus.
Melissa Krizia Vieri, Adam Hendy, John L. Mokili, Robert Colebunders   +3 more
doaj   +1 more source

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza, Michael Olubusayo Binuyo, Callixte Cyuzuzo, Acsa Igizeneza, Jean Paul Sinumvayo, Oluwaremilekun Grace Ajakaye, Egie Elisha Enabulele, Zororo Chinwadzimba, Ezera Agwu, Nicholas Midzi   +9 more
wiley   +1 more source

Lords of the flies: dipteran migrants are diverse, abundant and ecologically important

Biological Reviews, Volume 100, Issue 4, Page 1635-1659, August 2025.
ABSTRACT Insect migrants are hugely abundant, with recent studies identifying the megadiverse order Diptera as the major component of many migratory assemblages. Despite this, their migratory behaviour has been widely overlooked in favour of more ‘charismatic’ migrant insects such as butterflies, dragonflies, and moths.
Will L. Hawkes, Myles H.M. Menz, Karl R. Wotton   +2 more
wiley   +1 more source

Onchocerca volvulus is not detected in the cerebrospinal fluid of persons with onchocerciasis-associated epilepsy

International Journal of Infectious Diseases, 2020
Objectives: Epidemiological evidence links onchocerciasis with the development of epilepsy. The aim of this study was to detect Onchocerca volvulus microfilariae or its bacterial endosymbiont, Wolbachia, in the cerebrospinal fluid (CSF) of persons with ...
An Hotterbeekx, Stephen Raimon, Gasim Abd-Elfarag, Jane Y. Carter, Wilson Sebit, Abozer Suliman, Joseph Nelson Siewe Fodjo, Peter De Witte, Makoy Yibi Logora, Robert Colebunders, Samir Kumar-Singh   +10 more
doaj   +1 more source