Co-infection with Onchocerca volvulus and Loa loa microfilariae in central Cameroon: are these two species interacting? [PDF]
Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L.
Pion, SDS +13 more
core +1 more source
Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle [PDF]
Ivermectin (Mectizan, Merck and CO. Inc.) is being widely used in the control of human onchocerciasis (Onchoverca volvulus) because of its potent effect on microfilariae.
Barend M deC Bronsvoort +15 more
core +1 more source
Nodding syndrome (NS) and Onchocerca Volvulus (OV) in Northern Uganda
Nodding Syndrome (NS) is a childhood neurological disorder characterized by atonic seizures, cognitive decline, school dropout, muscle weakness, thermal dysfunction, wasting and stunted growth.
David Kitara Lagoro, Denis Anywar Arony
doaj +1 more source
Após caracterização clínico-epidemiológica da oncocercose na região Yanomâmi, RR, Brasil, iniciada em 1993, a Fundação Nacional de Saúde (FNS) implementou um projeto piloto de controle e tratamento nos pólos de base de Tootobi e Balawaú.
Giovanini E. Coelho +4 more
doaj +1 more source
Observações preliminares sobre a transmissão de oncocercose no rio Toototobi, Amazonas, Brasil [PDF]
Resumo Em dezembro de 1975 os autores estudaram vários fatores que influenciam a transmissão de Onchocerca volvulus ao norte do Amazonas, no rio Toototobi. Observaram que a densidade de microfilarias de O.
A. J. Shelley +2 more
doaj +1 more source
Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.
Two major human diseases caused by filariid nematodes are onchocerciasis, or river blindness, and lymphatic filariasis, which can lead to elephantiasis.
Christina A Bulman +24 more
doaj +1 more source
A simple isothermal DNA amplification method to screen black flies for Onchocerca volvulus infection. [PDF]
Onchocerciasis is a debilitating neglected tropical disease caused by infection with the filarial parasite Onchocerca volvulus. Adult worms live in subcutaneous tissues and produce large numbers of microfilariae that migrate to the skin and eyes.
Andy Alhassan +4 more
doaj +1 more source
Microfilarial distribution of Loa loa in the human host: population dynamics and epidemiological implications. [PDF]
Severe adverse events (SAEs) following ivermectin treatment may occur in people harbouring high Loa loa microfilarial (mf) densities. In the context of mass ivermectin distribution for onchocerciasis control in Africa, it is crucial to define precisely ...
Pion, Sébastien +11 more
core +1 more source
Extracellular Onchocerca-derived small RNAs in host nodules and blood
Background microRNAs (miRNAs), a class of short, non-coding RNA can be found in a highly stable, cell-free form in mammalian body fluids. Specific miRNAs are secreted by parasitic nematodes in exosomes and have been detected in the serum of murine and ...
Juan F Quintana +13 more
doaj +1 more source
Globally, epilepsy is the most common chronic neurological disorder. The incidence in sub-Saharan Africa is 2-3 times higher than that in high income countries.
Rodney Ogwang +21 more
doaj +1 more source

