Results 31 to 40 of about 14,649 (169)

Simuliidae and the transmission and control of human Onchocerciasis in Latin America

Cadernos de Saúde Pública, 1991
Factors that affect the propensity of a simuliid species to act as a host to Onchocerca volvulus and to naturally transmit this filarial worm in nature are discussed.
A. J. Shelley
doaj   +1 more source

Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With Onchocerca ochengi

Frontiers in Cellular and Infection Microbiology, 2022
Human onchocerciasis is a devastating neglected tropical disease caused by infection of the filarial nematode Onchocerca volvulus. The infection can cause irreversible visual impairment or blindness and stigmatizing dermatitis.
Bin Zhan, Maria Elena Bottazzi, Peter J. Hotez, Sara Lustigman   +3 more
doaj   +1 more source

Onchocerca volvulus dan Loa loa [PDF]

, 2023
Filaria merupakan cacing dari filum Nematoda dan merupakan beberapa diantaranya merupakan parasit pada manusia yang secara umum disebut sebagai filariasis.
Ronny, Ronny
core   +1 more source

Prevalence and risk factors for Active Convulsive Epilepsy in Kintampo, Ghana

The Pan African Medical Journal, 2015
INTRODUCTION: epilepsy is common in sub-Saharan Africa, but there is little data in West Africa, to develop public health measures for epilepsy in this region.
Kenneth Ayuurebobi Ae-Ngibise, Bright Akpalu, Anthony Ngugi, Albert Akpalu, Francis Agbokey, Patrick Adjei, Damien Punguyire, Christian Bottomley, Charles Newton, Seth Owusu-Agyei   +9 more
doaj   +1 more source

Immunological genomics of Brugia malayi:filarial genes implicated in immune evasion and protective immunity [PDF]

, 2001
Filarial nematodes are metazoan parasites with genome sizes of> 100 million base pairs, probably encoding 15 000-20 000 genes. Within this considerable gene complement, it seems likely that filariae have evolved a spectrum of immune evasion products ...
Scott, Alan, Scott, A L, Maizels, Rick, Blaxter, Mark   +3 more
core   +1 more source

Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90 [PDF]

, 2010
The chemotherapy of lymphatic filariasis relies upon drugs such as diethylcarbamazine and ivermectin that largely target the microfilarial stages of the parasite, necessitating continued treatment over the long reproductive life span of the adult worm ...
Gillan, V., O'Neill, K., Devaney, E., Chiosis Gabriela, Kerry O'Neill, Taldone, T., Devaney Eileen, Taldone Tony, Patel, P., O'Neill Kerry, Rodina, A., Kirsty Maitland, Chiosis, G., Maitland Kirsty, Anna Rodina, Rodina Anna, Victoria Gillan, Tony Taldone, Pallav Patel, Gillan Victoria, Sun, W., Eileen Devaney, Patel Pallav, Weilin Sun, Gabriela Chiosis, Maitland, K., Sun Weilin   +26 more
core   +2 more sources

Assessments of the transmission of Onchocerca volvulus by Simulium sanctipauli in the Upper Denkyira District, Ghana, and the intermittent disappearance of the vector.

, 2015
Following studies on the transmission of Onchocerca volvulus (Leuckart) by Simulium sanctipauli Vajime & Dunbar (Diptera, Simuliidae) in Upper Denkyira District in Ghana in 2001 and 2002 (Kutin et al., Med Vet Ent 18:167-173, 2004), further assessments ...
Baffour-Awuah, S, Nagel, M, Kruppa, TF, Biritwum, NK, Post, RJ, Debrah, AY, Adjei, O, Garms, R, Owusu-Dabo, E, Gankpala, L, Badu, K   +10 more
core   +1 more source

The Functional Parasitic Worm Secretome: Mapping the Place of Onchocerca volvulus Excretory Secretory Products

Pathogens, 2020
Nematodes constitute a very successful phylum, especially in terms of parasitism. Inside their mammalian hosts, parasitic nematodes mainly dwell in the digestive tract (geohelminths) or in the vascular system (filariae). One of their main characteristics
Luc Vanhamme, Jacob Souopgui, Stephen Ghogomu, Ferdinand Ngale Njume   +3 more
doaj   +1 more source

Unraveling cross-reactivity of anti-glycan IgG responses in filarial nematode infections

Frontiers in Immunology, 2023
Parasitic nematodes responsible for filarial diseases cause chronic disablement in humans worldwide. Elimination programs have substantially reduced the rate of infection in certain areas, but limitations of current diagnostics for population ...
Laudine M. C. Petralia, Laudine M. C. Petralia, Angela van Diepen, Dieu-Linh Nguyen, Lena A. Lokker, Erliyani Sartono, Sasisekhar Bennuru, Thomas B. Nutman, Kenneth Pfarr, Kenneth Pfarr, Achim Hoerauf, Achim Hoerauf, Samuel Wanji, Jeremy M. Foster, Cornelis H. Hokke   +14 more
doaj   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source