Results 11 to 20 of about 14,649 (169)

Exposure to multiple parasites is associated with the prevalence of active convulsive epilepsy in sub-Saharan Africa. [PDF]

PLoS Neglected Tropical Diseases, 2014
BackgroundEpilepsy is common in developing countries, and it is often associated with parasitic infections. We investigated the relationship between exposure to parasitic infections, particularly multiple infections and active convulsive epilepsy (ACE ...
Gathoni Kamuyu, Christian Bottomley, James Mageto, Brett Lowe, Patricia P Wilkins, John C Noh, Thomas B Nutman, Anthony K Ngugi, Rachael Odhiambo, Ryan G Wagner, Angelina Kakooza-Mwesige, Seth Owusu-Agyei, Kenneth Ae-Ngibise, Honorati Masanja, Faith H A Osier, Peter Odermatt, Charles R Newton, Study of Epidemiology of Epilepsy in Demographic Sites (SEEDS) group   +17 more
doaj   +2 more sources

Phylogenetic relationships of the Wolbachia of nematodes and arthropods. [PDF]

PLoS Pathogens, 2006
Wolbachia are well known as bacterial symbionts of arthropods, where they are reproductive parasites, but have also been described from nematode hosts, where the symbiotic interaction has features of mutualism.
Katelyn Fenn, Claire Conlon, Martin Jones, Michael A Quail, Nancy E Holroyd, Julian Parkhill, Mark Blaxter   +6 more
doaj   +3 more sources

Not every worm wrapped around a stick is a guinea worm: a case of Onchocerca volvulus mimicking Dracunculus medinensis

Parasites & Vectors, 2015
Background Despite being certified guinea worm free in 2007, Cameroon continues surveillance efforts to ensure rapid verification of any suspected reoccurrence.
Eta Ngole Mbong, Gerald Etapelong Sume, Flaubert Danbe, Walter Kang Kum, Valeri Oben Mbi, André Arsène Bita Fouda, Peter Atem   +6 more
doaj   +2 more sources

The mitogenome of Onchocerca volvulus from the Brazilian Amazonia focus [PDF]

Memorias do Instituto Oswaldo Cruz, 2016
We report here the first complete mitochondria genome of Onchocerca volvulus from a focus outside of Africa. An O. volvulus mitogenome from the Brazilian Amazonia focus was obtained using a combination of high-throughput and Sanger sequencing ...
James L Crainey, Túllio RR da Silva, Fernando Encinas, Michel A Marín, Ana Carolina P Vicente, Sérgio LB Luz   +5 more
doaj   +2 more sources

Effects of emodepside on single-channel properties of Onchocerca volvulus SLO-1A (BK) potassium channels. [PDF]

Parasit Vectors
Background: Control of onchocerciasis (river blindness of humans due to infection with the filarial nematode, Onchocerca volvulus) remains a challenge because of the lack of effective adulticides and vaccines.
Njeshi CN, Choudhary S, McHugh MA, Kashyap SS, Robertson AP, Martin RJ.   +5 more
europepmc   +2 more sources

Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis.

PLoS Pathogens, 2021
Onchocerciasis (river blindness), caused by the filarial worm Onchocerca volvulus, is a neglected tropical disease mostly affecting sub-Saharan Africa and is responsible for >1.3 million years lived with disability. Current control relies almost entirely
Germanus S Bah, Sebastian Schneckener, Steffen R Hahnel, Nicolas H Bayang, Helena Fieseler, Gabriele M Schmuck, Ralph Krebber, Anouk Sarr, Carsten Terjung, Henrietta F Ngangyung, David D Ekale, Youssouf M Mfopit, Lucien Rufener, John Graham-Brown, Vincent N Tanya, Martin Glenschek-Sieberth, Daniel Kulke, Benjamin L Makepeace   +17 more
doaj   +1 more source

Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells. [PDF]

PLoS ONE, 2012
Ivermectin is currently approved for treatment of both clinical and veterinary infections by nematodes, including Onchocerca cervicalis in horses and Onchocerca volvulus in humans.
Matthew A Pettengill, Verissa W Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, David M Ojcius   +4 more
doaj   +1 more source

Serotonin Levels in the Serum of Persons with Onchocerciasis-Associated Epilepsy: A Case-Control Study

Pathogens, 2021
Onchocerciasis-associated epilepsy (OAE) is a devastating childhood disorder occurring in areas with high Onchocerca volvulus transmission. Despite epidemiological evidence showing the association between O.
Melissa Krizia Vieri, An Hotterbeekx, Michel Mandro, Joseph Nelson Siewe Fodjo, Alfred Dusabimana, Francoise Nyisi, Deby Mukendi, Joe Gwatsvaira, Samir Kumar-Singh, Robert Colebunders   +9 more
doaj   +1 more source

Surveillance for Onchocerciasis-Associated Epilepsy and OV16 IgG4 Testing of Children 6–10 Years Old Should Be Used to Identify Areas Where Onchocerciasis Elimination Programs Need Strengthening

Pathogens, 2022
To eliminate onchocerciasis-associated morbidity, it is important to identify areas where there is still high ongoing Onchocerca volvulus transmission.
Alfred Dusabimana, Joseph Nelson Siewe Fodjo, Michel Mandro Ndahura, Bruno P. Mmbando, Stephen Raimon Jada, Annelies Boven, Eric De Smet, Tony Ukety, Alfred K. Njamnshi, Anne Laudisoit, Steven Abrams, Robert Colebunders   +11 more
doaj   +1 more source

Rates of microfilarial production by Onchocerca volvulus are not cumulatively reduced by multiple ivermectin treatments. [PDF]

, 2008
Regular distribution of ivermectin reduces onchocerciasis transmission and morbidity by killing, within humans, the microfilarial stage of the parasite (microfilaricidal effect).
Bottomley, Christian, Isham, Valerie, Collins, Richard C, Basáñez, Maria-Gloria   +3 more
core   +1 more source