Results 11 to 20 of about 577,954 (290)
Dietary fat intake and liver cancer risk: A prospective cohort study in Chinese women
Objective: This study aimed to determine whether dietary fat intake increased liver cancer risk in Chinese women from a prospective population-based cohort.
Xiaowei Ji +8 more
doaj +1 more source
No abstract available.
Rita de Cassia Stocco +3 more
openaire +4 more sources
The central problem in cancer therapy is the poor selectivity of current systemic agents against the common solid tumours. The demonstration that unique segments of DNA, constant in location and conserved in evolution are involved in growth control opens new avenues for basic and clinical research.
+8 more sources
Abstract Cancer cells contain multiple genetic and epigenetic abnormalities. Despite this complexity, their growth and survival can often be impaired by the inactivation of a single oncogene. This phenomenon, called “oncogene addiction,” provides a rationale for molecular targeted therapy.
I Bernard, Weinstein, Andrew, Joe
openaire +2 more sources
Insulin-like growth factors (IGFs) play important roles in mammalian growth, development, aging, and diseases. Aberrant IGFs signaling may lead to malignant transformation and tumor progression, thus providing the rationale for targeting IGF axis in ...
Hui Hua +4 more
doaj +1 more source
Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy
Cancer microenvironment is critical for tumorigenesis and cancer progression. The extracellular matrix (ECM) interacts with tumor and stromal cells to promote cancer cells proliferation, migration, invasion, angiogenesis and immune evasion.
Yangfu Jiang +5 more
doaj +1 more source
Mechanisms for estrogen receptor expression in human cancer
Estrogen is a steroid hormone that has critical roles in reproductive development, bone homeostasis, cardiovascular remodeling and brain functions. However, estrogen also promotes mammary, ovarian and endometrial tumorigenesis.
Hui Hua +3 more
doaj +1 more source
To understand the importance of frequent deletions at chromosome 11q24.1‐24.2 region in breast carcinoma, alterations (deletion/methylation) of the candidate genes LOH11CR2A, ROBO3, ROBO4, HEPACAM, PIG8 and CHEK1 located in this region were analyzed in ...
Satyabrata Sinha +8 more
doaj +1 more source
Coffee drinking and cancer risk: an umbrella review of meta-analyses of observational studies
Background Epidemiological studies on the association between coffee intake and cancer risk have yielded inconsistent results. To summarize and appraise the quality of the current evidence, we conducted an umbrella review of existing findings from meta ...
Long-Gang Zhao +7 more
doaj +1 more source
Correction to: Elf3 drives β-catenin transactivation and associates with poor prognosis in colorectal cancer [PDF]
J.-L. Wang +10 more
doaj +2 more sources

