Results 11 to 20 of about 577,954 (290)

Dietary fat intake and liver cancer risk: A prospective cohort study in Chinese women

open access: yesCancer Biology & Medicine, 2022
Objective: This study aimed to determine whether dietary fat intake increased liver cancer risk in Chinese women from a prospective population-based cohort.
Xiaowei Ji   +8 more
doaj   +1 more source

Oncogenic Processes [PDF]

open access: yesBioMed Research International, 2014
No abstract available.
Rita de Cassia Stocco   +3 more
openaire   +4 more sources

Oncogenes

open access: yesScandinavian Journal of Gastroenterology, 1985
The central problem in cancer therapy is the poor selectivity of current systemic agents against the common solid tumours. The demonstration that unique segments of DNA, constant in location and conserved in evolution are involved in growth control opens new avenues for basic and clinical research.
  +8 more sources

Oncogene Addiction [PDF]

open access: yesCancer Research, 2008
Abstract Cancer cells contain multiple genetic and epigenetic abnormalities. Despite this complexity, their growth and survival can often be impaired by the inactivation of a single oncogene. This phenomenon, called “oncogene addiction,” provides a rationale for molecular targeted therapy.
I Bernard, Weinstein, Andrew, Joe
openaire   +2 more sources

Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy

open access: yesJournal of Hematology & Oncology, 2020
Insulin-like growth factors (IGFs) play important roles in mammalian growth, development, aging, and diseases. Aberrant IGFs signaling may lead to malignant transformation and tumor progression, thus providing the rationale for targeting IGF axis in ...
Hui Hua   +4 more
doaj   +1 more source

Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy

open access: yesJournal of Hematology & Oncology, 2022
Cancer microenvironment is critical for tumorigenesis and cancer progression. The extracellular matrix (ECM) interacts with tumor and stromal cells to promote cancer cells proliferation, migration, invasion, angiogenesis and immune evasion.
Yangfu Jiang   +5 more
doaj   +1 more source

Mechanisms for estrogen receptor expression in human cancer

open access: yesExperimental Hematology & Oncology, 2018
Estrogen is a steroid hormone that has critical roles in reproductive development, bone homeostasis, cardiovascular remodeling and brain functions. However, estrogen also promotes mammary, ovarian and endometrial tumorigenesis.
Hui Hua   +3 more
doaj   +1 more source

RETRACTED: Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1‐24.2 region in breast carcinoma: Clinical and prognostic implications

open access: yesMolecular Oncology, 2011
To understand the importance of frequent deletions at chromosome 11q24.1‐24.2 region in breast carcinoma, alterations (deletion/methylation) of the candidate genes LOH11CR2A, ROBO3, ROBO4, HEPACAM, PIG8 and CHEK1 located in this region were analyzed in ...
Satyabrata Sinha   +8 more
doaj   +1 more source

Coffee drinking and cancer risk: an umbrella review of meta-analyses of observational studies

open access: yesBMC Cancer, 2020
Background Epidemiological studies on the association between coffee intake and cancer risk have yielded inconsistent results. To summarize and appraise the quality of the current evidence, we conducted an umbrella review of existing findings from meta ...
Long-Gang Zhao   +7 more
doaj   +1 more source

Correction to: Elf3 drives β-catenin transactivation and associates with poor prognosis in colorectal cancer [PDF]

open access: yesCell Death and Disease
J.-L. Wang   +10 more
doaj   +2 more sources

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