Results 201 to 210 of about 617,669 (345)
Specific inhibition of tyrosine kinase activity by an antibody to the v-ros oncogene product [PDF]
P C Balduzzi+3 more
openalex +1 more source
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen+13 more
wiley +1 more source
Fusion oncogenes in rhabdomyosarcoma: model systems, mechanisms of tumorigenesis, and therapeutic implications. [PDF]
Sankhe CS, Hall L, Kendall GC.
europepmc +1 more source
Cancer of the exocrine pancreas: from oncogenes to unrespectable tumors. Frontiers of gastrointestinal research. Vol 12 [PDF]
K. G. Wormsley
openalex +1 more source
NDRG1 drives lactate accumulation and histone lactylation in lung adenocarcinoma, promoting immunosuppression via M2 macrophage polarization and CD8⁺ T cell inhibition. High NDRG1 expression correlates with poor prognosis, an immunosuppressive microenvironment, and immunotherapy resistance.
Gujie Wu+14 more
wiley +1 more source
Evaluating Tumor Dynamics Using Circulating Tumor DNA in the Rare Cancer Anorectal Malignant Melanoma: A Report of Two Cases. [PDF]
Takahashi G+12 more
europepmc +1 more source
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang+18 more
wiley +1 more source
The roles, signalling pathways and therapeutic implications of Apoc1 in cancer. [PDF]
Guo HH, Guo Q, Zhang QX, Li D, Lv Y.
europepmc +1 more source