Results 201 to 210 of about 846,916 (323)

Sidedness matters: Colon cancer outcomes in low-resource settings. [PDF]

World J Clin Oncol
González-Montero J, Valenzuela G, Rojas CI, Burotto M.   +3 more
europepmc   +1 more source

ras Oncogene Activation of a VL30 Transcriptional Element Is Linked to Transformation

, 1990
Russell D. Owen, Donna M. Bortner, Michael C. Ostrowski   +2 more
openalex   +2 more sources

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Editorial Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma

Molecular Cancer
Satyabrata Sinha, Ratnesh K. Singh, Neyaz Alam, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda   +5 more
doaj   +1 more source

Colorectal cancer tumor phenotypes associated with <i>KRAS</i>, <i>NRAS</i>, and <i>BRAF</i> hot-spot mutations. [PDF]

World J Gastrointest Pathophysiol
Abdelgadir O, Kuo YF, Khan MF, Okorodudu AO, Cheng YO, Dong J.   +5 more
europepmc   +1 more source

Modulatory effect of the transmembrane domain of the protein-tyrosine kinase encoded by oncogene ros: biological function and substrate interaction.

, 1994
Cong S. Zong, L H Wang
openalex   +2 more sources

Bosutinib therapy through the TGF-ß1 signaling pathway activity can increase apoptosis of BCR-ABL oncogene positive cells

, 2022
Masoomeh Bakhshayesh, Fereshteh Golab, Hanie Bakhshayesh, Ladan Hosseini Gohari, Gelareh Vahabzade   +4 more
openalex   +1 more source

KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression

Advanced Science, EarlyView.
Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao, Matthew F. Yee, Chaitanya N. Parikh, Boyang Ma, Yueying Cao, Yu‐Huan Shih, Joae Qiong Wu, Marcus Ruscetti, Shun‐Qing Liang, Wen Xue   +9 more
wiley   +1 more source

Prevalence, molecular characterization, and prognosis of c-Met protein overexpression in a real-world cohort of patients with non-squamous non-small cell lung cancer. [PDF]

Acta Oncol
Bar J, Cai MH, Choi YC, Baijal S, Zhao W, Liede A, Vasilopoulos A, Roberts-Rapp L, Jiang F, Simmons A, Ratajczak C, Lu S, Ansell PJ, Camidge DR.   +13 more
europepmc   +1 more source

Differential expression of transforming growth factor-beta 1 (TGF-beta 1) receptors in murine myeloid cell lines transformed with oncogenes. Correlation with differential growth inhibition by TGF-beta 1

, 1991
Maria C. Birchenall-Roberts, L A Falk, James Kasper, Jonathan Keller, CR Faltynek, F W Ruscetti   +5 more
openalex   +1 more source