Results 221 to 230 of about 846,916 (323)

Retraction Note: Fermitin family member 2 promotes melanoma progression by enhancing the binding of p-α-Pix to Rac1 to activate the MAPK pathway. [PDF]

Oncogene
Huang S, Deng W, Wang P, Yan Y, Xie C, Cao X, Chen M, Zhang C, Shi D, Dong Y, Cheng P, Xu H, Zhu W, Hu Z, Tang B, Zhu J.   +15 more
europepmc   +1 more source

CypA Mediates Non‐Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11

Advanced Science, EarlyView.
Summary diagram for the role of CypA in chemoresistance in non‐small cell lung cancer (NSCLC). CypA is overexpressed in chemoresistance NSCLC and drives therapeutic evasion by competitively binding to the K37 site of SLC7A11, thereby blocking TRIM3 mediated K11‐linked ubiquitination and proteasomal degradation, ultimately inhibiting lipid peroxidation ...
Zhongcheng Wang, An Li, Ziwei Song, Xiangming Liu, Yong Ge, Zhiqiao Chen, Yuhui Liu, Boyu Zhang, Hao Zhang, Ting Lan   +9 more
wiley   +1 more source

Molecular genetics of development studied in the transgenic mouse. [PDF]

, 1989
Gruss, P., Westphal, H.
core   +2 more sources

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

A Nomogram for Predicting Lung Metastasis in Papillary Thyroid Cancer Patients Aged Less Than 55 Years. [PDF]

Front Endocrinol (Lausanne)
Yang H, Qian Q, Li Y, Pan W, Peng J, Zou Z, Zhu H, Shi F.   +7 more
europepmc   +1 more source

982 Pharmacologic oncogene pathway agonism to sensitize RAS-mutant cancers to immunotherapy [PDF]

Álvaro de Mingo Pulido, Charles H. Adelmann, Leticia Tordesillas, Karol Prieto, Brittney Sell, Omar Chavez-Chiang, Francisca Beato, Jason B. Fleming, Karen M. Mann, Kenneth Y. Tsai   +9 more
openalex   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Exposure to Occupational Carcinogens and Non-Oncogene Addicted Phenotype in Lung Cancer: Results from a Real-Life Observational Study. [PDF]

Cancers (Basel)
Oddone E, D'Amato L, Pernetti R, Madeo D, Toschi L, Farinatti S, Riva G, Spina L, Ferrante L, Conde C, Locati LD, Sottotetti F, Barbic F.   +12 more
europepmc   +1 more source

Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation [PDF]

, 2004
CULP, LA, EDSJO, A, KARLSSON, J, NILSSON, H, PAHLMAN, S, Pattyn, Filip, Speleman, Franki, Vandesompele, Jo   +7 more
core   +2 more sources

Function of Deubiquitinating Enzyme USP14 as Oncogene in Different Types of Cancer [PDF]

, 2016
Ying Zhu, Chaoxiong Zhang, Changxin Gu, Qiang Li, Ning Wu   +4 more
openalex   +1 more source