Results 251 to 260 of about 369,580 (326)
Targeted Therapy for a Rare PDGFRB-Rearranged Myeloproliferative Neoplasm: A Case Report. [PDF]
Barbato C +19 more
europepmc +1 more source
Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley +1 more source
KMT2A-rearranged leukemia: from mechanism to drug development. [PDF]
Ernst P, S Kyei P, Yokoyama A.
europepmc +1 more source
Extramedullary Disease—Achilles Heel in Myeloma?
ABSTRACT Despite advances in therapy, extramedullary disease (EMD) remains an aggressive form of multiple myeloma associated with poor outcomes. Patients with true EMD, in which plasmacytomas have become completely independent of bone, have a particularly poor prognosis. The pathogenesis of EMD is driven by complex mechanisms involving loss of adhesion
Shaji Kumar +7 more
wiley +1 more source
TRPS1::PLAG1 Fusion in a Primary Cutaneous Myoepithelial Carcinoma: A Case Report and Literature Review. [PDF]
Gillis T, Howell J, Jafarian F.
europepmc +1 more source
Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets [PDF]
et al,, Li, Shunqiang, Shao, Jieya
core +1 more source
Abstract Extracellular vesicles (EVs) derived from pluripotent stem cells have been reported to reprogram cancer cells to a more benign phenotype, due to its provision of an embryonic microenvironment. Here, we show that the effect of the EVs on the tumorigenicity of the cancer cell lines is cell type‐dependent.
Chan Du +3 more
wiley +1 more source
Rare FUS::FEV-Rearranged Adamantinoma-Like Ewing Sarcoma Arising in the Submandibular Gland. [PDF]
Agboola T, Miller DL.
europepmc +1 more source
The plant oncogene rolC is responsible for the release of cytokinins from glucoside conjugates.
J. J. Estruch +4 more
semanticscholar +1 more source

