Results 121 to 130 of about 2,503,880 (309)

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

open access: yesAdvanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho   +13 more
wiley   +1 more source

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

open access: yesAdvanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li   +17 more
wiley   +1 more source

The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin   +10 more
wiley   +1 more source

Identification of adenovirus E1A gene regions involved in chemosensitisation of prostate cancer cells [PDF]

open access: yes, 2009
PhDReplication-selective adenoviruses are promising anti-cancer therapies (virotherapy). Viruses can be engineered to selectively target cancer cells by deleting viral genes involved in cell cycle regulation.
Rota, Enrique Miranda
core   +2 more sources

Modulation of replication of simian virus 40 by oncogene proteins.

open access: yes, 1991
Modulation of replication of simian virus 40 by oncogene ...
Na-Gyong. Lee (7977053)
core   +3 more sources

Human cytomegalovirus and mucoepidermoid carcinoma of salivary glands: Cell-specific localization of active viral and oncogenic signaling proteins is confirmatory of a causal relationship

open access: yesExperimental and Molecular Pathology, 2012
Human cytomegalovirus (hCMV) infection is common. Although still controversial, there is growing evidence that active hCMV infection is associated with a variety of malignancies, including brain, breast, lung, colon, and prostate. Given that hCMV is frequently resident in salivary gland (SG) ductal epithelium, we hypothesized that hCMV would be ...
Michael, Melnick   +3 more
openaire   +2 more sources

BRAF (v-raf murine sarcoma viral oncogene homolog B1

open access: yes, 2004
Review on BRAF (v-raf murine sarcoma viral oncogene homolog B1, with data on DNA, on the protein encoded, and where the gene is ...
Domingo, E, Schwartz, S Jr
core   +1 more source

HPV-18 transformed cells fail to arrest in G1 in response to quercetin treatment [PDF]

open access: yes, 2005
Previous work with primary human keratinocytes demonstrated that quercetin, a potent mutagen found in high levels in bracken fern (Pteridium aquilinum), arrested cells in G1 with concomitant elevation of the cyclin-dependent kinase inhibitor (cdki ...
Beniston, R.G., Campo, M.S.
core   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao   +10 more
wiley   +1 more source

Concentration of soluble form of hepatocyte growth factor receptor in cerebrospinal fluid and serum of patients with bacterial and viral meningitis

open access: yesMedical Laboratory Journal, 2012
Background and objectives: C-Met is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). The HGF receptor possesses tyrosine -kinase activity and it is essential for embryonic development, wound healing and cancer ...
Khoshdel Rad N   +2 more
doaj  

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