Results 131 to 140 of about 2,503,880 (309)

The potato mop-top virus TGB2 protein and viral RNA associate with chloroplasts and viral infection induces inclusions in the plastids [PDF]

, 2012
The potato mop-top virus (PMTV) triple gene block 2 (TGB2) movement proteins fused to monomeric red fluorescent protein (mRFP-TGB2) was expressed under the control of the PMTV subgenomic promoter from a PMTV vector.
Roberts, Alison G., Cowan, Graham H., Angelika eZiegler, Ziegler, Angelika, Eugene I Savenkov, Lesley eTorrance, Angelika Ziegler, Lesley Torrance, Alison G Roberts, Torrance, Lesley, Sean N. Chapman, Graham H Cowan, Chapman, Sean N., Savenkov, Eugene I., Sean N Chapman, Alison G. Roberts, Chapman, Sean, Graham H. Cowan, Eugene I. Savenkov, Savenkov, Eugene, Sveriges lantbruksuniversitet., Savenkov, Eugene,, Swedish University of Agricultural Sciences.   +22 more
core   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) [PDF]

, 1999
Review on KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog), with data on DNA, on the protein encoded, and where the gene is ...
Larizza, L, L. Larizza, A. Beghini, Beghini, A, A Beghini, L Larizza   +5 more
core   +1 more source

RBM25 Drives Hepatocellular Carcinoma Progression by Stabilizing YAP Through Regulating Oncogenic Splicing‐switch of MYPT1

Advanced Science, EarlyView.
This study establishes that the RBM25‐PRPF40A interaction modulates MYPT1 splicing, promoting the production of the oncogenic long isoform. This isoform stabilizes YAP by suppressing its phosphorylation and subsequent proteasomal degradation, ultimately accelerating tumor growth.
Wenjing Zhang, Lili Zhi, Tian Huang, Lingya Feng, Chaoqun Chen, Huanhuan Wei, Xiaolong Liu, Lei Chen, Jinrui Zhang, Ge Zhang, Baofeng Zhao, Rong Liu, Dan Chen, Yangfan Qi, Yang Wang   +14 more
wiley   +1 more source

The role of PML proteins in adenovirus type 5 infection and the type I interferon response [PDF]

Promyelocytic leukaemia (PML) proteins consist of a collection of related isoforms that are the nucleating components of sub-nuclear structures termed PML nuclear bodies (PML NBs). Numerous functions are attributed to PML and PML NBs, including a role
Wright, Jordan
core  

ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)) [PDF]

, 2012
Review on ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)), with data on DNA, on the protein encoded, and where the gene is ...
Awasthi, S, Hamburger, AW
core   +1 more source

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang, Shuangyue Pan, Lu Bai, Bin Li, Tiantian Liu, Jianing Cao, Mengdi Yang, Heda Zhang, Duancheng Guo, Wenxiang Zhi, Zhonghua Tao, Xichun Hu   +11 more
wiley   +1 more source

Regulation and function of the HPV16 CircE7 RNA

Journal of Virology
High-risk human papillomaviruses (HPV), including HPV16, produce circular RNA that encompasses the E7 oncogene (circE7). CircE7 can be detected in HPV16-positive cells and tumors, is preferentially localized to the cytoplasm, is N6-methyladenosine (m6A ...
Eunice E. Lee, Yihui Huang, Eleanor Dowell, Kaitlyn Walsh, Calvin Hosler, Austin Witt, Odera Ifeacho, Doreen Palsgrove, Andrew Day, Claire James, Richard C. Wang   +10 more
doaj   +1 more source

The Use of Intrinsic Disorder and Phosphorylation by Oncogenic Viral Proteins to Dysregulate the Host Cell Cycle Through Interaction with pRb

Viruses
Approximately 15% of cancers worldwide are caused by oncogenic viruses. These infectious agents utilize multiple strategies to dysregulate their host cells as a means of viral reproduction. While this typically involves a small number of viral oncoproteins known to interact with a myriad of host cell proteins, direct binding with the tumor suppressor ...
Heidi Kast-Woelbern, Sarah K. Martinho, Kayla T. Julio, Audrey M. Vazzana, Abbey E. Mandagie, Ariane L. Jansma   +5 more
openaire   +3 more sources

Utilising proteomic approaches to understand oncogenic human herpesviruses [PDF]

, 2014
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population.
Owen, Christopher B, Hughes, DJ, Berndt, Anja, Schumann, Sophie, Whitehouse, A, Jackson, BR, Whitehouse, Adrian, Baquero-Perez, Belinda, Jackson, Brian R, Berndt, A, Owen, CB, Hughes, David J, Baquero-Perez, B, Schumann, S, Hughes, David J; id_orcid   +14 more
core   +1 more source