Results 261 to 270 of about 2,503,880 (309)

Early-Onset Colorectal Cancer With Liver-Only Metastases: A Retrospective Cohort Study Integrating Prospectively Collected Real-World Clinical and Molecular Data From an Australian National Database (2009-2024) to Guide Treatment Planning. [PDF]

Med J Aust
Barreto SG, Karapetis CS, Ullah S, Burge M, Caird S, Campbell A, Jalali A, Jennens R, Khattak MA, Lee B, Lim SH, Mendis S, Nott L, Price TJ, Shapiro JD, Tie J, Torres J, Williams C, Wong R, Wong V, Gibbs P.   +20 more
europepmc   +1 more source

High-fat diet-responsive DNM1 promotes hepatocellular carcinoma progression and predicts poor prognosis in viral-associated patients. [PDF]

Am J Cancer Res
Chen PM, Huang HY, Chen HH, Chen RF, Chiang EI.   +4 more
europepmc   +1 more source

Pseudorabies virus pUL40 drives inflammatory signaling through competitive hijacking of EphA2 from the Akt-EphA2 interaction. [PDF]

Vet Res
Tian Y, Yin H, Fu J, Yang Q, Yan R, Li Y, Ye C, Fang R.   +7 more
europepmc   +1 more source

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Human oncogenic viruses: an overview of protein biomarkers in viral cancers and their potential use in clinics

Expert Review of Anticancer Therapy, 2022
Although the idea that carcinogenesis might be caused by viruses was first voiced about 100 years ago, today's data disappointingly show that we have not made much progress in preventing and/or treating viral cancers in a century. According to recent studies, infections are responsible for approximately 13% of cancer development in the world. Today, it
Medi Kori, Kazim Yalcin Arga
openaire   +3 more sources

Identification of nuclear proteins encoded by viral and cellular myc oncogenes

Nature, 1983
The myelocytomatosis viruses are a family of replication-defective avian retroviruses that cause a variety of tumours in chickens and transform both fibroblasts and macrophages in culture through the activity of their oncogene v-myc. A closely related gene (c-myc) is found in vertebrate animals and is thought to be the progenitor of v-myc.
K, Alitalo, G, Ramsay, J M, Bishop, S O, Pfeifer, W W, Colby, A D, Levinson   +5 more
openaire   +2 more sources

Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery

Journal of Cellular Physiology, 2012
AbstractThe retinoblastoma (RB) family consists of three genes, RB1, RBL1, and RBL2, that code for the pRb, p107, and pRb2/p130 proteins, respectively. All these factors have pivotal roles in controlling fundamental cellular mechanisms such as cell cycle, differentiation and apoptosis.
Emanuele, Bellacchio, Marco G, Paggi
openaire   +2 more sources

Structural Characterization of HBXIP: The Protein That Interacts with the Anti-Apoptotic Protein Survivin and the Oncogenic Viral Protein HBx

Journal of Molecular Biology, 2011
Hepatitis B X-interacting protein (HBXIP) is a ubiquitous protein that was originally identified as a binding partner of the hepatitis B viral protein HBx. HBXIP is also thought to serve as an anti-apoptotic cofactor of survivin, promoting the suppression of pro-caspase-9 activation. Here were port the crystal structure of the shortest isoform of HBXIP
I, Garcia-Saez, F B, Lacroix, D, Blot, F, Gabel, D A, Skoufias   +4 more
openaire   +2 more sources