Results 61 to 70 of about 2,503,880 (309)
MYB (v-myb myeloblastosis viral oncogene homolog (avian)) [PDF]
, 2010 Review on MYB (v-myb myeloblastosis viral oncogene homolog (avian)), with data on DNA, on the protein encoded, and where the gene is ...
Diwakar Ram Pattabiraman +8 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Mouse Mammary Tumor Virus Molecular Biology and Oncogenesis
Viruses, 2010 Mouse mammary tumor virus (MMTV), which was discovered as a milk‑transmitted, infectious cancer-inducing agent in the 1930s, has been used since that time as an animal model for the study of human breast cancer.
Susan R. Ross
doaj +1 more source
Abrogation of the Brd4-Positive Transcription Elongation Factor b Complex by Papillomavirus E2 Protein Contributes to Viral Oncogene Repression [PDF]
Journal of Virology, 2010 ABSTRACT The cellular bromodomain protein Brd4 is a major interacting partner of the papillomavirus (PV) E2 protein. Interaction of E2 with Brd4 contributes to viral episome maintenance. The E2-Brd4 interaction also plays an important role in repressing viral oncogene expression from the integrated viral genome in human PV (HPV)-positive ...
Yan, Junpeng +4 more
openaire +3 more sources
REL (v-rel reticuloendotheliosis viral oncogene homolog (avian)) [PDF]
, 2002 Review on REL (v-rel reticuloendotheliosis viral oncogene homolog (avian)), with data on DNA, on the protein encoded, and where the gene is ...
F Chen, Chen, F
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The use of fluorescence microscopy to study the association between herpesviruses and intrinsic resistance factors [PDF]
, 2011 Intrinsic antiviral resistance is a branch of antiviral defence that involves constitutively expressed cellular proteins that act within individual infected cells.
Roger D. Everett +2 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
MODERN ASPECTS OF HUMAN PAPILLOMAVIRUS VACCINATION
Безопасность и риск фармакотерапии, 2018 Human papillomavirus refers to DNA-containing viruses and infects the skin and mucosal epithelium. One common way is to change the expression of cellular genes by integrating the viral genome into cellular DNA.
O. S. Alyautdina, M. A. Darmostukova
doaj +1 more source
Role of RAS signaling in ovarian cancer [version 1; peer review: 2 approved]
F1000Research, 2022 The RAS family of proteins is among the most frequently mutated genes in human malignancies. In ovarian cancer (OC), the most lethal gynecological malignancy, RAS, especially KRAS mutational status at codons 12, 13, and 61, ranges from 6–65% spanning ...
Hesham M. Korashy +5 more
doaj +1 more source