Results 41 to 50 of about 2,503,880 (309)
The Kaposi's sarcoma‐associated herpesvirus G protein‐coupled receptor: Lessons on dysregulated angiogenesis from a viral oncogene [PDF]
Journal of Cellular Biochemistry, 2010 Abstract Tumor viruses can induce cell transformation by overcoming cellular defense mechanisms and promoting the ungoverned proliferation of infected cells. To this end, functionally related viral oncogenes have evolved in disparate viruses to over‐ride key proliferative and survival intracellular pathways, thus assuring efficient ...
Bruno C, Jham, Silvia, Montaner
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RELB (v-rel reticuloendotheliosis viral oncogene homolog B) [PDF]
, 2002 Review on RELB (v-rel reticuloendotheliosis viral oncogene homolog B), with data on DNA, on the protein encoded, and where the gene is ...
Chen, F
core +1 more source
Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis
Viruses, 2010 Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes both in vitro and in vivo.
Patrick L. Green, Priya Kannian
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Molecules, 2020 This short review is focused on enzymatic properties of human ATP-dependent RNA helicase DDX3 and the development of antiviral and anticancer drugs targeting cellular helicases.
Marina K. Kukhanova +2 more
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HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation. [PDF]
PLoS Pathogens, 2014 The human T-cell leukemia virus type 1 (HTLV-1) Tax protein hijacks the host ubiquitin machinery to activate IκB kinases (IKKs) and NF-κB and promote cell survival; however, the key ubiquitinated factors downstream of Tax involved in cell transformation ...
Young Bong Choi, Edward William Harhaj
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MYCN (v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)) [PDF]
, 2012 Review on MYCN (v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)), with data on DNA, on the protein encoded, and where the gene is ...
Kolla, V +3 more
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Frontiers in Immunology, 2022 Adult T-cell leukemia/lymphoma (ATL) is a T-cell lymphoproliferative neoplasm caused by the human T-cell leukemia virus type 1 (HTLV-1). Two viral proteins, Tax-1 and HBZ play important roles in HTLV-1 infectivity and in HTLV-1-associated pathologies by ...
Mariam Shallak +10 more
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Antiapoptotic and Oncogenic Potentials of Hepatitis C Virus Are Linked to Interferon Resistance by Viral Repression of the PKR Protein Kinase [PDF]
Journal of Virology, 1999 ABSTRACTHepatitis C virus (HCV) is prevalent worldwide and has become a major cause of liver dysfunction and hepatocellular carcinoma. The high prevalence of HCV reflects the persistent nature of infection and the large frequency of cases that resist the current interferon (IFN)-based anti-HCV therapeutic regimens.
M, Gale +4 more
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AKT2 (v-akt murine thymoma viral oncogene homolog 2) [PDF]
, 2008 Review on AKT2 (v-akt murine thymoma viral oncogene homolog 2), with data on DNA, on the protein encoded, and where the gene is ...
Altomare, DA, Testa, JR
core +1 more source
Viruses, 2020 Viruses alter a multitude of host-cell processes to create a more optimal environment for viral replication. This includes altering metabolism to provide adequate substrates and energy required for replication.
Martin A. Prusinkiewicz +7 more
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