Results 111 to 120 of about 30,889 (150)
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New England Journal of Medicine, 2008
This review — the first in a series concerning the biology of cancer — is a comprehensive survey of oncogenes, tumor-suppressor genes, and microRNA genes in cancer cells. Work on the recently discovered microRNA genes in malignant cells has revealed new complexities in the regulation of oncogenes and tumor-suppressor genes and new opportunities for the
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This review — the first in a series concerning the biology of cancer — is a comprehensive survey of oncogenes, tumor-suppressor genes, and microRNA genes in cancer cells. Work on the recently discovered microRNA genes in malignant cells has revealed new complexities in the regulation of oncogenes and tumor-suppressor genes and new opportunities for the
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1998
Virulent strains of Agrobacterium tumefaciens and Agrobacterium rhizogenes induce non-self limiting — neoplastic — growths on susceptible plants, generally in dicotyledonous species from the Angiosperms. In most cases, A. tumefaciens induces unorganized “crown gall” tumors (so named because the growths were often observed at the crown of the plant ...
BINNS A. N., COSTANTINO, Paolo
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Virulent strains of Agrobacterium tumefaciens and Agrobacterium rhizogenes induce non-self limiting — neoplastic — growths on susceptible plants, generally in dicotyledonous species from the Angiosperms. In most cases, A. tumefaciens induces unorganized “crown gall” tumors (so named because the growths were often observed at the crown of the plant ...
BINNS A. N., COSTANTINO, Paolo
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Oncogenes and proto-oncogenes: General concepts
1989Theoretically, the cancerous phenotype of cells can result from epigenetic or biochemical regulatory changes without alteration of the genotype. Although epigenetic changes may contribute to neoplasia, overwhelming evidence supports the concept that neoplasia results from heritable changes allowing unrestrained growth of cells that are associated with ...
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Current Opinion in Genetics & Development, 2006
MicroRNAs (miRNAs) are a class of non-coding RNAs that function as endogenous triggers of the RNA interference pathway. Originally discovered in Caenorhabditis elegans, this group of tiny RNAs has moved to the forefront of biology. With over 300 miRNA genes identified in the human genome, and a plethora of predicted mRNA targets, it is believed that ...
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MicroRNAs (miRNAs) are a class of non-coding RNAs that function as endogenous triggers of the RNA interference pathway. Originally discovered in Caenorhabditis elegans, this group of tiny RNAs has moved to the forefront of biology. With over 300 miRNA genes identified in the human genome, and a plethora of predicted mRNA targets, it is believed that ...
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1985
Publisher Summary Oncogenes are a set of cellular and viral genes that induce morphologic transformation and/or neoplastic changes in cells in which they are either activated or introduced in activated form. Their oncogenic properties are defined by the particular cells and biological test systems that are used to detect their presence.
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Publisher Summary Oncogenes are a set of cellular and viral genes that induce morphologic transformation and/or neoplastic changes in cells in which they are either activated or introduced in activated form. Their oncogenic properties are defined by the particular cells and biological test systems that are used to detect their presence.
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Targeting Oncogene and Non-Oncogene Addiction to Inflame the Tumour Microenvironment
Nature Reviews Drug Discovery, 2022Giulia Petroni +2 more
exaly
The MYC Oncogene — The Grand Orchestrator of Cancer Growth and Immune Evasion
Nature Reviews Clinical Oncology, 2022Renumathy Dhanasekaran +2 more
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ecDNA Hubs Drive Cooperative Intermolecular Oncogene Expression
Nature, 2021Kathryn E Yost, Ryan Corces, Sihan Wu
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