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Editorial: Editors’ showcase: insights in cancer cell biology
Frontiers in Cell and Developmental BiologyGeoffrey Brown, Andrew Liss, Andrew Liss
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Editorial: Novelties in acute myeloid leukemia: from biology to clinical applications
Frontiers in OncologyLuca Vincenzo Cappelli +4 more
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Factores de riesgo de cáncer bucal
Revista Cubana de EstomatologíaPedro Antonio Miguel Cruz +3 more
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The Journal of Pathology, 1984
A barrage of information is now emerging about one of the thorniest and most significant problems in biology: the nature of the genetic events that trigger neoplasia. While the notion that cancer reflects somatic mutations is several decades old, only in the last few years could the relevant 'oncogenes' be identified and put to molecular dissection ...
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A barrage of information is now emerging about one of the thorniest and most significant problems in biology: the nature of the genetic events that trigger neoplasia. While the notion that cancer reflects somatic mutations is several decades old, only in the last few years could the relevant 'oncogenes' be identified and put to molecular dissection ...
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Journal of Cellular Physiology, 1983
The discovery that normal cells contain proto-oncogenes--genes that are analogous to known viral oncogenes--may provide a shortcut not only to understanding some of the pathophysiologic mechanisms that must be involved in carcinogenesis but also to dissecting the processes of normal cell growth and of the evolutionarily developed controls on such ...
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The discovery that normal cells contain proto-oncogenes--genes that are analogous to known viral oncogenes--may provide a shortcut not only to understanding some of the pathophysiologic mechanisms that must be involved in carcinogenesis but also to dissecting the processes of normal cell growth and of the evolutionarily developed controls on such ...
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Current Opinion in Cell Biology, 1990
The study of oncogenes offers insights into many steps in signal transduction. Rapid progress is possible because of the combination of biochemistry and genetics--unique in vertebrate cell biology--the availability of specific clones and antibodies, sequence information, dominant mutants, and biochemical assays of function.
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The study of oncogenes offers insights into many steps in signal transduction. Rapid progress is possible because of the combination of biochemistry and genetics--unique in vertebrate cell biology--the availability of specific clones and antibodies, sequence information, dominant mutants, and biochemical assays of function.
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Cancer Letters, 1988
Particular eukaryotic genes which play integral roles in the control of normal growth and differentiation programs are targets for mutagenic events which lead to the generation of malignancies. These genes, called proto-oncogenes can be activated to the oncogenic state by amplification, point mutation, deletion or chromosomal translocation. The protein
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Particular eukaryotic genes which play integral roles in the control of normal growth and differentiation programs are targets for mutagenic events which lead to the generation of malignancies. These genes, called proto-oncogenes can be activated to the oncogenic state by amplification, point mutation, deletion or chromosomal translocation. The protein
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Seminars in Musculoskeletal Radiology, 2002
Oncogenic osteomalacia is a rare paraneoplastic syndrome caused by bone and soft tissue tumors. The characteristic clinical, metabolic, and imaging findings are reviewed, as is the radiologist's role in evaluation and diagnosis. New insight into the pathophysiology of oncogenic osteomalacia is also presented.
Kelli Andresen, Edmister +1 more
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Oncogenic osteomalacia is a rare paraneoplastic syndrome caused by bone and soft tissue tumors. The characteristic clinical, metabolic, and imaging findings are reviewed, as is the radiologist's role in evaluation and diagnosis. New insight into the pathophysiology of oncogenic osteomalacia is also presented.
Kelli Andresen, Edmister +1 more
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The marriage of oncogenes and anti-oncogenes
Trends in Genetics, 1988One of the more gratifying trends in oncogene/growth factor research has been the recent convergence of many initially unconnected investi- gations. Studies of retroviral onco- genes and cellular growth factors have merged as many of these onco- genes have been found to be homolo- gous with genes for growth factors or growth factor receptors. Similarly,
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