Results 161 to 170 of about 177,226 (290)

Initial biomarker testing strategies and clinical outcomes in advanced non-small cell lung cancer. [PDF]

iScience
Ishida M, Yamada T, Goto Y, Otsuki T, Taniguchi H, Harada T, Yoshimura A, Shiotsu S, Okada A, Jinno K, Kanda H, Inoguchi N, Fukui M, Yamada T, Hata T, Kawachi H, Katayama Y, Morimoto K, Iwasaku M, Kijima T, Takayama K.   +20 more
europepmc   +1 more source

Molecular targeting of HPV oncogenes and oncogenic protein

, 2010
THESIS 8974Worldwide cervical cancer is the second most common cause of cancer related death in women. Over the last three decades high-risk HPV has been conclusively established as the major etiological factor in cervical cancer and the expression of ...
Spillane, Cathy
core  

MicroRNA‐941 Acts as a Novel Prognostic Predictor and Oncogenic Driver in Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Upregulation of miR‐941 was a promising diagnostic and prognostic biomarker for CRC patients. Inhibition of miR‐941 significantly suppressed CRC cellular events and triggered ferroptosis. The oncogenic functions of miR‐941 were mediated through targeting TRPS1.
Hong Li, Yang Liu, Hua Chen, Jialin Li, Xinchun Li, Yanmin Chen   +5 more
wiley   +1 more source

Self‐Assembled Pt(II) Complexes Boost Up Stem Cell Proliferation and Accelerate Metamorphosis in Living Organisms

Angewandte Chemie, EarlyView.
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini, Tania Pecoraro, Anna Lewinska, Maciej Wnuk, Olga Kolodziej, Daniela Intartaglia, Simona Morgera, Alessandro Aliprandi, Giulia Veronesi, Giorgio Facchetti, Isabella Rimoldi, Angela Tino, Claudia Tortiglione, Luisa De Cola   +13 more
wiley   +2 more sources

Pervasive tissue specificity of driver genes revealed by mutational analysis of 265 cancer types. [PDF]

iScience
Chen J, Collins RL, Haigis KM.
europepmc   +1 more source

Biological Resectability in Colorectal Liver Metastases: A Nomogram‐Based Continuous Risk Model to Define Borderline Disease

Annals of Gastroenterological Surgery, EarlyView.
KRAS mutation demonstrated a prognostic impact according to primary tumor sidedness, independent of tumor morphology, in patients undergoing hepatectomy for colorectal liver metastases. A nomogram integrating biological and clinicopathological factors was developed to provide continuous biological risk assessment.
Yuzo Umeda, Toshiharu Mitsuhashi, Tomokazu Fuji, Toru Kojima, Takeshi Koujima, Tatsuo Matsuda, Daisuke Satoh, Masaru Inagaki, Kosei Takagi, Toshiyoshi Fujiwara   +9 more
wiley   +1 more source

Hybrid extrachromosomal DNA in HPV-driven cancers. [PDF]

J Virol
Hafey B, Xie L.
europepmc   +1 more source

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo, Jinyin Yan, Wenli Li, Jin Wang, Lu Liu, Chengmei Zhang, Wei Cao, Shanshan Yao, Haibo Gong, Yi He, Zihan Zhou, Siyan Chen, Li Feng, Haijing Deng   +13 more
wiley   +1 more source

Frequency and Risk Factors for Secondary Malignancies in Patients with Mycosis Fungoides

Turkish Journal of Hematology, 2017
Fatma Pelin Cengiz, Nazan Emiroğlu, Nahide Onsun   +2 more
doaj   +1 more source

Integrating single-cell transcriptomics to construct an oncogene-driven prognostic model and elucidate metabolic-immune crosstalk in hepatocellular carcinoma. [PDF]

Mol Cell Oncol
Wang Z, Xu Z, Zhang M, Akram H, Guan Z, Li L.   +5 more
europepmc   +1 more source