Results 221 to 230 of about 250,918 (350)

Specific inhibition of tyrosine kinase activity by an antibody to the v-ros oncogene product [PDF]

, 1986
P C Balduzzi, Meirav Chovav, J. Christensen, Ian G. Macara   +3 more
openalex   +1 more source

Application of non‑coding RNAs in tumors (Review). [PDF]

Mol Med Rep
Zhang Z, Mao C, Wu Y, Wang Y, Cong H.
europepmc   +1 more source

EccDNA‐Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation

Advanced Science, EarlyView.
Following ionizing radiation, eccDNA‐mediated VPS41 amplification slightly increases its expression but fails to prevent apoptosis. Introducing exogenous eccDNA or VPS41 enhances VPS41‐KAI1 interaction, promoting lysosomal degradation of KAI1. This process inhibits apoptotic signaling, enhancing cell survival and resistance to radiation‐induced damage.
Bin Shi, Ping Yang, Huaijin Qiao, Jinchen He, Bin Song, Hao Bai, Fengdi Jiang, Yining Zhang, Qian Li, Tao Yan, Wenlin Tu, Daojiang Yu, Shuyu Zhang   +12 more
wiley   +1 more source

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences [PDF]

, 1984
Julian Downward, Yosef Yarden, E. L. V. Mayes, Geoffrey Scrace, Nicholas F. Totty, Peter A. Stockwell, A. Ullrich, Joseph Schlessinger, Michael D. Waterfield   +8 more
openalex   +1 more source

Editorial: New strategies for treating fusion-driven sarcomas. [PDF]

Front Cell Dev Biol
Espinosa-Cotton M, Lee SB, Patel AG.
europepmc   +1 more source

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non‐small Cell Lung Cancer

Advanced Science, EarlyView.
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin, Yongbiao Huang, Bin Li, Yuan Wang, Yan Li, Zhirui Chen, Zhe Tang, Chaofan Liu, Lei Zhang, Xianglin Yuan, Jianbo Tian, Bo Liu   +11 more
wiley   +1 more source

Avian sarcoma virus 17 carries the jun oncogene.

, 1987
Maki Yoshio, Timothy J. Bos, Charles E. Davis, Michael W. Starbuck, Peter K. Vogt   +4 more
openalex   +1 more source

Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis. [PDF]

Stem Cell Res Ther
Montilla-Rojo J, Hillenius S, Eleveld TF, Salvatori DCF, Looijenga LHJ.   +4 more
europepmc   +1 more source

Identification and Drug Screening of Single Cells from Human Tumors on Semiconductor Chip for Cancer Precision Medicine

Advanced Science, EarlyView.
The study innovatively integrates single‐cell electric impedance identification and drug screening on a semiconductor chip, addressing tumor heterogeneity limitations. The system achieves label‐free cancer cell recognition while concurrently evaluating drug efficacy on cancer cells and toxicity on noncancerous cells.
Wenhao Hui, Ka‐Meng Lei, Yingying Liu, Xinru Huang, Yunlong Zhong, Xiaojun Chen, Mingji Wei, Jie Yan, Ren Shen, Pui‐In Mak, Rui P. Martins, Shuhong Yi, Ping Wang, Yanwei Jia   +13 more
wiley   +1 more source

Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene

, 1987
Richard Breathnach, Lynn M. Matrisian, Marie-Claude Gesnel, Adrien Staub, Pierre Leroy   +4 more
openalex   +1 more source