Results 261 to 270 of about 384,141 (378)

Activation of spinal MrgC-Gi-NR2B-nNOS signaling pathway by Mas oncogene-related gene C receptor agonist bovine adrenal medulla 8-22 attenuates bone cancer pain in mice.

, 2016
Yue Sun, Juan Zhang, Yishan Lei, Cui’e Lu, Bailing Hou, Zhengliang Ma, Xiaoping Gu   +6 more
openalex   +1 more source

Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice

Science, 2012
D. Friedmann-Morvinski, E. Bushong, Eugene Ke, Y. Soda, Tomotoshi Marumoto, O. Singer, Mark Ellisman, I. Verma   +7 more
semanticscholar   +1 more source

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

Advanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi, Yunqing Lu, Xing Chang, Ying Wang, Jiawang Zhou, Guoyou Xie, Lijun Tao, Zhaotong Wang, Yifan Tian, Lihong Wang, Feng Tang, Yijing Zheng, Xinchen Yue, Jinping Lei, Xiansong Wang, Lichen Ge, Zhuojia Chen, Hongsheng Wang   +17 more
wiley   +1 more source

Database of recurrent mutations, an unbiased web resource to browse recurrent mutations in cancers. [PDF]

iScience
Chakroborty D, Vaparanta K, Ghimire B, Paatero I, Kurppa KJ, Elenius K.   +5 more
europepmc   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

Genetic and epigenetic contribution to tamoxifen resistance in breast cancer, concepts to drive therapeutic strategies. [PDF]

Discov Oncol
Jahangiri R.
europepmc   +1 more source

Oncogene addiction [PDF]

Current Biology, 2012
openaire   +2 more sources

New targetable oncogenes in non-small-cell lung cancer.

Journal of Clinical Oncology, 2013
G. Oxnard, A. Binder, P. Jänne
semanticscholar   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Prevalence by Age and Predictors of Medullary Thyroid Cancer in Patients with Lower Risk Germline RET Proto-Oncogene Mutations

, 2014
Thereasa A. Rich, Lei Feng, Naifa L. Busaidy, Gilbert J. Cote, Robert F. Gagel, Mimi I. Hu, Camilo Jiménez, Jeffrey E. Lee, Nancy D. Perrier, Steven I. Sherman, Steven G. Waguespack, Anita K. Ying, Elizabeth G. Grubbs   +12 more
openalex   +1 more source