Results 51 to 60 of about 384,141 (378)

Post‐operative mortality and recurrence patterns in pancreatic cancer according to KRAS mutation and CDKN2A, p53, and SMAD4 expression

The Journal of Pathology: Clinical Research, 2023
Alterations in KRAS, CDKN2A (p16), TP53, and SMAD4 genes have been major drivers of pancreatic carcinogenesis. The clinical course of patients with pancreatic cancer in relation to these driver alterations has not been fully characterised in large ...
Yohei Masugi, Manabu Takamatsu, Mariko Tanaka, Kensuke Hara, Yosuke Inoue, Tsuyoshi Hamada, Tatsunori Suzuki, Junichi Arita, Yuki Hirose, Yoshikuni Kawaguchi, Yousuke Nakai, Atsushi Oba, Naoki Sasahira, Gaku Shimane, Tsuyoshi Takeda, Keisuke Tateishi, Sho Uemura, Mitsuhiro Fujishiro, Kiyoshi Hasegawa, Minoru Kitago, Yu Takahashi, Tetsuo Ushiku, Kengo Takeuchi, Michiie Sakamoto, for the GTK Pancreatic Cancer Study Group in Japan   +24 more
doaj   +1 more source

Coagulation in Brain Tumors: Biological Basis and Clinical Implications

Frontiers in Neurology, 2019
Cancer patients commonly show abnormal laboratory coagulation tests, indicating a subclinical hypercoagulable condition that contribute to morbidity and mortality.
Chiara Mandoj, Luigi Tomao, Laura Conti
doaj   +1 more source

Hsa-miR-133a-3p, miR-1-3p, GOLPH3 and JUP combination results in a good biomarker to distinguish between prostate cancer and non-prostate cancer patients

Frontiers in Oncology, 2022
The incidence and mortality of Prostate Cancer (PCa) worldwide correlate with age and bad dietary habits. Previously, we investigated the mRNA/miRNA role on PCa development and progression using high fat diet (HFD) fed mice.
Rocío Belén Duca, Cintia Massillo, Paula Lucía Farré, Karen Daniela Graña, Juana Moro, Kevin Gardner, Ezequiel Lacunza, Adriana De Siervi   +7 more
doaj   +1 more source

High MYC mRNA expression is more clinically relevant than MYC DNA amplification in triple-negative breast cancer [PDF]

, 2019
DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC).
Dasgupta, Subhamoy, Katsuta, Eriko, McDonald, Kerry-Ann, Opyrchal, Mateusz, Takabe, Kazuaki, Takeshita, Takashi, Yan, Li   +6 more
core   +2 more sources

DNA replication stress: oncogenes in the spotlight

Genetics and Molecular Biology, 2019
Precise replication of genetic material is essential to maintain genome stability. DNA replication is a tightly regulated process that ensues faithful copies of DNA molecules to daughter cells during each cell cycle.
Luiza M. F. Primo, Leonardo K Teixeira
semanticscholar   +1 more source

Immunological Response against Breast Lineage Cells Transfected with Human Papillomavirus (HPV)

Viruses
Breast cancer is the most common neoplasm worldwide. Viral infections are involved with carcinogenesis, especially those caused by oncogenic Human Papillomavirus (HPV) genotypes.
Daffany Luana Santos, Bianca de França São Marcos, Georon Ferreira de Sousa, Leonardo Carvalho de Oliveira Cruz, Bárbara Rafaela da Silva Barros, Mariane Cajuba de Britto Lira Nogueira, Talita Helena de Araújo Oliveira, Anna Jessica Duarte Silva, Vanessa Emanuelle Pereira Santos, Cristiane Moutinho Lagos de Melo, Antonio Carlos de Freitas   +10 more
doaj   +1 more source

Emerging Biomarkers for Predicting Bladder Cancer Lymph Node Metastasis

Frontiers in Oncology, 2021
Bladder cancer is one of the leading causes of cancer deaths worldwide. Early detection of lymph node metastasis of bladder cancer is essential to improve patients’ prognosis and overall survival.
Chunyu Zhang, Jiao Hu, Huihuang Li, Hongzhi Ma, Belaydi Othmane, Wenbiao Ren, Wenbiao Ren, Zhenglin Yi, Dongxu Qiu, Zhenyu Ou, Jinbo Chen, Xiongbing Zu   +11 more
doaj   +1 more source

Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells [PDF]

, 2016
Bovine papillomavirus (BPV) types 1 and 2 play an important role in the pathogenesis of equine sarcoids (ES), the most common cutaneous tumour affecting horses.
Britton, C., Nasir, L., Nicolson, L., Terron-Canedo, N., Weir, W.   +4 more
core   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source